Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 3/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | MERTK | Q12866 | 7/20 | 0.31 |
| ▸ | AXL | P30530 | 5/20 | 0.31 |
| ▸ | MET | P08581 | 2/20 | 0.31 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25117861 | 0.94 | ALDH1A1 (0.33) | NTRK1JAK2TYK2L3MBTL1KDM4E | |
| SCHEMBL25839690 | 0.85 | JAK2 (0.35) | NTRK1JAK2TYK2L3MBTL1KDM4E | |
| SCHEMBL30309824 | 0.84 | ALDH1A1 (0.34) | NTRK1JAK2TYK2L3MBTL1KDM4E | |
| SCHEMBL25839563 | 0.84 | ALDH1A1 (0.34) | NTRK1JAK2TYK2L3MBTL1KDM4E | |
| SCHEMBL25118112 | 0.83 | ALDH1A1 (0.39) | TYK2L3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL25118141 | 0.81 | ALDH1A1 (0.33) | TYK2L3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL25839766 | 0.81 | ALDH1A1 (0.33) | TYK2L3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL25118111 | 0.77 | ALDH1A1 (0.34) | L3MBTL1KDM4EALDH1A1HPGDMAPK1 | |
| SCHEMBL25839577 | 0.75 | ALDH1A1 (0.35) | NTRK1JAK2L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL25839689 | 0.75 | JAK2 (0.33) | NTRK1JAK2L3MBTL1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219978-A1 | COMPOUND HAVING MACROCYCLIC STRUCTURE AND USE THEREOF | SCINNOHUB PHARMACEUTICAL CO., LTD (CN) | 2023-07-13 | — | — | US | disclosed |
| EP-4163283-A1 | COMPOUND HAVING MACROCYCLIC STRUCTURE AND USE THEREOF | Scinnohub Pharmaceutical Co., Ltd (CN) | 2023-04-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219978-A1 | COMPOUND HAVING MACROCYCLIC STRUCTURE AND USE THEREOF | BTK, SRC, YES1 | NTRK1 768/4885JAK2 9/4885TYK2 24/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.