Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 2/20 | 0.38 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.33 |
| ▸ | CLK2 | P49760 | 2/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 3/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.32 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.31 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.31 |
| ▸ | CYP3A7 | P24462 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22988110 | 0.96 | KDM5A (0.36) | KDM5APAK1PIM1AKT1KDM5B | |
| SCHEMBL22988111 | 0.85 | CLK2 (0.36) | PAK1CLK2LRRK2PIM1JAK2 | |
| SCHEMBL22987760 | 0.85 | CLK2 (0.34) | KDM5APAK1CLK2LRRK2PIM1 | |
| SCHEMBL22987741 | 0.84 | PIK3CD (0.41) | PIK3CDPIK3R1 | |
| SCHEMBL22988153 | 0.84 | IRAK4 (0.36) | CLK2LRRK2PIM1JAK2JAK1 | |
| SCHEMBL30393332 | 0.83 | CHRNB2 (0.37) | PAK1PIM1JAK2PIK3CDCYP1A2 | |
| SCHEMBL22988265 | 0.83 | CHRNB2 (0.37) | PAK1PIM1JAK2PIK3CDCYP1A2 | |
| SCHEMBL22988018 | 0.83 | ADORA2A (0.42) | — | |
| SCHEMBL22987742 | 0.80 | JAK2 (0.37) | KDM5AAKT1JAK2TYK2 | |
| SCHEMBL22979970 | 0.80 | PIK3CD (0.33) | AKT1JAK2PIK3CDTYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230113037-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230113037-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | AHR, HRH4, HRH1 | KDM5A 378/4885PAK1 1770/4885CLK2 1689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.