SCHEMBL25119403

SCHEMBL25119403

N#Cc1ccc(-c2ccc3c(c2)c2ccccc2n3-c2cccc(-c3ccccc3)c2)c2c1C1c3ccccc3C2c2ccccc21

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
HPGD P15428 1/20 0.33
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CYP11B1 P15538 1/20 0.32
CYP11B2 P19099 1/20 0.32
TSPO P30536 1/20 0.31
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30
GABRA1 P14867 1/20 0.30
GABRG2 P18507 1/20 0.30
GABRB3 P28472 1/20 0.30
GABRA5 P31644 1/20 0.30
GABRA3 P34903 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25119452 0.95 KDM4E (0.37) KDM4EATML3MBTL1ALDH1A1LMNA
SCHEMBL25119071 0.94 KDM4E (0.39) KDM4EATML3MBTL1ALDH1A1LMNA
SCHEMBL25119411 0.93 KDM4E (0.35) KDM4EATML3MBTL1ALDH1A1LMNA
SCHEMBL25119017 0.93 KDM4E (0.40) KDM4EATML3MBTL1ALDH1A1LMNA
SCHEMBL25119021 0.93 CYP11B1 (0.35) KDM4EATML3MBTL1ALDH1A1LMNA
SCHEMBL25119449 0.93 KDM4E (0.36) KDM4EATML3MBTL1ALDH1A1LMNA
SCHEMBL25119442 0.91 KDM4E (0.38) KDM4EATML3MBTL1ALDH1A1LMNA
SCHEMBL25119436 0.90 L3MBTL1 (0.43) KDM4EATML3MBTL1ALDH1A1TSPO
SCHEMBL25565084 0.89 KDM4E (0.33) KDM4EATML3MBTL1ALDH1A1LMNA
SCHEMBL25119066 0.86 L3MBTL1 (0.40) KDM4EATML3MBTL1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023052272-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-04-06 WO disclosed