Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | BAD | Q92934 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 3/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.34 |
| ▸ | STS | P08842 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4970027 | 0.96 | BCL2L1 (0.47) | BCL2L1BADXDHSLC22A12AR | |
| SCHEMBL21567337 | 0.78 | NOTUM (0.40) | ALDH1A1MAPK1HSD17B10KDM4EALOX15 | |
| SCHEMBL27995892 | 0.77 | S1PR1 (0.33) | BCL2L1BADXDHSLC22A12ALDH1A1 | |
| SCHEMBL23105986 | 0.75 | AR (0.41) | XDHSLC22A12ARALDH1A1MAPK1 | |
| SCHEMBL16239399 | 0.74 | BCL2L1 (0.52) | BCL2L1BADMEN1KMT2APARP1 | |
| SCHEMBL16702241 | 0.73 | BCL2L1 (0.42) | BCL2L1BADPARP1 | |
| SCHEMBL22102581 | 0.73 | NOTUM (0.43) | ALDH1A1MAPK1HSD17B10KDM4ELMNA | |
| SCHEMBL29660345 | 0.73 | NOTUM (0.43) | ALDH1A1MAPK1HSD17B10KDM4ELMNA | |
| SCHEMBL1535927 | 0.73 | BCL2L1 (0.50) | BCL2L1BAD | |
| SCHEMBL25837417 | 0.73 | KDM4E (0.37) | XDHSLC22A12ALDH1A1MAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4159736-A1 | NOVEL TRICYCLIC AROMATIC HETEROCYCLIC COMPOUND AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND USE THEREOF | Shanghai Longwood Biopharmaceuticals Co., Ltd. (CN) | 2023-04-05 | — | — | EP | disclosed |