SCHEMBL181208

SCHEMBL181208

CCCCCCCCCCCCCCCCCC[SiH2]CCCCCCCCCCCCCCCCCC

nearest known ligand 0.57

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.57
THRB P10828 1/20 0.57
DNM1 Q05193 9/20 0.50
ALDH1A1 P00352 3/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
EPHX1 P07099 1/20 0.50
LMNA P02545 2/20 0.42
HSD17B10 Q99714 1/20 0.42
SLC22A1 O15245 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2511627 1.00 TSHR (0.57) TSHRTHRBDNM1ALDH1A1MEN1
SCHEMBL67826 1.00 TSHR (0.57) TSHRTHRBDNM1ALDH1A1MEN1
SCHEMBL2510830 1.00 TSHR (0.57) TSHRTHRBDNM1ALDH1A1MEN1
SCHEMBL16209849 1.00 TSHR (0.57) TSHRTHRBDNM1ALDH1A1MEN1
SCHEMBL17386447 1.00 TSHR (0.57) TSHRTHRBDNM1ALDH1A1MEN1
SCHEMBL10803622 1.00 TSHR (0.57) TSHRTHRBDNM1ALDH1A1MEN1
SCHEMBL17386495 1.00 TSHR (0.57) TSHRTHRBDNM1ALDH1A1MEN1
SCHEMBL2512253 1.00 TSHR (0.57) TSHRTHRBDNM1ALDH1A1MEN1
SCHEMBL10841351 1.00 TSHR (0.57) TSHRTHRBDNM1ALDH1A1MEN1
SCHEMBL3397735 1.00 TSHR (0.57) TSHRTHRBDNM1ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3423808-B1 METHOD AND INSTRUMENT FOR EXTRACTING A COMPONENT FROM A SAMPLE JP SCIENT LIMITED (CA) 2023-08-16 EP claimed
CN-113164910-A Adsorbents, devices, kits and methods useful for biological sample processing 沃特世科技公司 2021-07-23 CN claimed
EP-0675900-B1 ANTIBIOTICS GE 37468 A, B AND C BIOSEARCH ITALIA SPA (IT) 1998-02-18 EP claimed
EP-0230052-B1 Immunoamplifiers and related Compositions GOTTLIEB ARTHUR A (US) 1994-04-06 EP claimed
EP-0128831-B1 DRUG ADMINISTRATION Carey, Martin C. (US) 1993-01-07 EP claimed
EP-0173889-B1 IMMUNOAMPLIFIERS AND PROCESSES FOR THE EXTRACTION THEREOF Gottlieb, Arthur A. (US) 1992-03-25 EP claimed
EP-0119574-B1 ANTIBIOTIC L 17046 AND PROCESS FOR PREPARING IT GRUPPO LEPETIT S.p.A. (IT) 1988-11-17 EP claimed
EP-0119575-B1 PURE PREPARATION OF ANTIBIOTIC L 17054 AND PROCESS FOR PREPARING IT GRUPPO LEPETIT S.p.A. (IT) 1988-08-03 EP claimed
EP-0109089-B1 PROCESS FOR PURIFYING MODULATORS OF THE IMMUNE SYSTEM Gottlieb, Arthur A. (US) 1988-03-02 EP claimed
CN-107406476-B Mononuclear iron complex and organic synthesis reaction using same 国立大学法人九州大学 2021-07-27 CN disclosed
EP-3269724-B1 MONONUCLEAR IRON COMPLEX AND ORGANIC SYNTHESIS REACTION USING SAME UNIV KYUSHU NAT UNIV CORP (JP) 2020-04-22 EP disclosed
EP-3118205-B1 MONONUCLEAR RUTHENIUM COMPLEX AND ORGANIC SYNTHESIS REACTION USING SAME UNIV KYUSHU NAT UNIV CORP (JP) 2020-04-22 EP disclosed
US-10363551-B2 Mononuclear iron complex and organic synthesis reaction using same KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2019-07-30 US disclosed
EP-2963047-B1 MONONUCLEAR IRON COMPLEX AND ORGANIC SYNTHESIS REACTION USING SAME UNIV KYUSHU NAT UNIV CORP (JP) 2018-11-14 EP disclosed
EP-2402348-A1 FIELD EFFECT TRANSISTOR Hiroshima University (JP) 2012-01-04 EP disclosed
US-20060287449-A1 Ultrahigh-molecular ethylene polymer ASAHI KASEI CHEMICALS CORPORATION (JP) 2006-12-21 US disclosed
EP-1483272-B1 UREA OR CARBAMATE DERIVATIVES OF CROWN ETHERS AND SILICON USEFUL FOR THE PREPARATION OF SUPPORTS FOR CHROMATOGRAPHIC SEPARATION OF METAL CATIONS AND ORGANIC MOLECULES COMPRISING AN AMINO FUNCTION COMMISSARIAT ENERGIE ATOMIQUE (FR) 2006-01-11 EP disclosed
EP-1605000-A1 ULTRAHIGH-MOLECULAR ETHYLENE POLYMER Asahi Kasei Chemicals Corporation (JP) 2005-12-14 EP disclosed
EP-1483272-A1 UREA OR CARBAMATE DERIVATIVES OF CROWN ETHERS AND SILICON USEFUL FOR THE PREPARATION OF SUPPORTS FOR CHROMATOGRAPHIC SEPARATION OF METAL CATIONS AND ORGANIC MOLECULES COMPRISING AN AMINO FUNCTION Commissariat à l'Energie Atomique (FR) 2004-12-08 EP disclosed
WO-2003062250-A1 UREA OR CARBAMATE DERIVATIVES OF CROWN ETHERS AND SILICON USEFUL FOR THE PREPARATION OF SUPPORTS FOR CHROMATOGRAPHIC SEPARATION OF METAL CATIONS AND ORGANIC MOLECULES COMPRISING AN AMINO FUNCTION COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2003-07-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10363551-B2 Mononuclear iron complex and organic synthesis reaction using same TFRC, IDO1, H1-0 TSHR 726/4885THRB 3513/4885DNM1 2801/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.