Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.34 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALKBH1 | Q13686 | 5/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25122875 | 1.00 | L3MBTL1 (0.52) | L3MBTL1CYP4F2CYP4A11TSHRHPGDS | |
| SCHEMBL25122913 | 1.00 | L3MBTL1 (0.52) | L3MBTL1CYP4F2CYP4A11TSHRHPGDS | |
| SCHEMBL30872639 | 0.92 | L3MBTL1 (0.48) | L3MBTL1CYP4F2CYP4A11TSHRPLA2G4A | |
| SCHEMBL25122904 | 0.86 | L3MBTL1 (0.40) | L3MBTL1TSHRCYP1A2CHRM2CHRM4 | |
| SCHEMBL27166456 | 0.86 | L3MBTL1 (0.40) | L3MBTL1TSHRCYP1A2CHRM2CHRM4 | |
| SCHEMBL25123873 | 0.86 | L3MBTL1 (0.40) | L3MBTL1TSHRCYP1A2CHRM2CHRM4 | |
| SCHEMBL25122887 | 0.77 | EGLN1 (0.53) | L3MBTL1CYP4F2CYP4A11HPGDSALKBH2 | |
| SCHEMBL28791760 | 0.76 | L3MBTL1 (0.59) | L3MBTL1CYP4F2CYP4A11HPGDSALKBH2 | |
| SCHEMBL2828291 | 0.75 | L3MBTL1 (0.68) | L3MBTL1CYP4F2CYP4A11HPGDSALKBH2 | |
| SCHEMBL26994038 | 0.74 | L3MBTL1 (0.58) | L3MBTL1CYP4F2CYP4A11HPGDSALKBH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4334307-A1 | CDK2 DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2024-03-13 | — | — | EP | disclosed |
| US-20230110180-A1 | CDK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-04-13 | — | — | US | disclosed |
| WO-2022236058-A1 | CDK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2022-11-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230110180-A1 | CDK2 DEGRADERS AND USES THEREOF | CDK2, CDK20, CDK1 | L3MBTL1 2534/4885CYP4F2 2249/4885CYP4A11 1724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.