Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 14/20 | 0.81 |
| ▸ | CCNB2 | O95067 | 9/20 | 0.81 |
| ▸ | CCNB1 | P14635 | 9/20 | 0.81 |
| ▸ | CCNB3 | Q8WWL7 | 9/20 | 0.81 |
| ▸ | CDK2 | P24941 | 7/20 | 0.81 |
| ▸ | CDK4 | P11802 | 2/20 | 0.81 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.81 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.81 |
| ▸ | CCND1 | P24385 | 2/20 | 0.81 |
| ▸ | MAPK3 | P27361 | 2/20 | 0.81 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.81 |
| ▸ | KDR | P35968 | 2/20 | 0.81 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.81 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.81 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.81 |
| ▸ | GSK3A | P49840 | 2/20 | 0.81 |
| ▸ | GSK3B | P49841 | 2/20 | 0.81 |
| ▸ | CSNK1G2 | P78368 | 2/20 | 0.81 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.81 |
| ▸ | CSNK1G1 | Q9HCP0 | 2/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25122463 | 0.90 | CDK1 (0.85) | CDK1CCNB2CCNB1CCNB3CDK2 | |
| SCHEMBL5098124 | 0.90 | CCNB2 (1.00) | CDK1CCNB2CCNB1CCNB3CDK2 | |
| SCHEMBL5726035 | 0.88 | CDK1 (0.81) | CDK1CCNB2CCNB1CCNB3CDK2 | |
| SCHEMBL5726034 | 0.88 | CDK1 (0.81) | CDK1CCNB2CCNB1CCNB3CDK2 | |
| SCHEMBL25122462 | 0.87 | CDK1 (0.80) | CDK1CCNB2CCNB1CCNB3CDK2 | |
| SCHEMBL5964864 | 0.86 | CDK1 (0.78) | CDK1CCNB2CCNB1CCNB3CDK2 | |
| SCHEMBL5725945 | 0.84 | CDK1 (0.72) | CDK1CCNB2CCNB1CCNB3CDK2 | |
| SCHEMBL26752090 | 0.83 | CCNB2 (0.74) | CDK1CCNB2CCNB1CCNB3CDK2 | |
| SCHEMBL25122994 | 0.81 | CDK1 (0.65) | CDK1CCNB2CCNB1CCNB3CDK2 | |
| SCHEMBL5964744 | 0.81 | CDK1 (0.70) | CDK1CCNB2CCNB1CCNB3CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230110180-A1 | CDK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230110180-A1 | CDK2 DEGRADERS AND USES THEREOF | CDK2, CDK20, CDK1 | CDK1 3/4885CCNB2 27/4885CCNB1 42/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.