SCHEMBL25123387

SCHEMBL25123387

CCOc1cc(F)cc(CCCCCC(=O)C(C)C)c1

nearest known ligand 0.45

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ CNR2 P34972 18/20 0.45
▸ CNR1 P21554 17/20 0.45
▸ CYP4F2 P78329 1/20 0.40
▸ CYP4A11 Q02928 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22525342 0.89 FFAR4 (0.40) CNR2CNR1CYP4F2CYP4A11
SCHEMBL25122747 0.86 CNR2 (0.46) CNR2CNR1
SCHEMBL27018353 0.85 CNR1 (0.47) CNR2CNR1CYP4F2CYP4A11
SCHEMBL25123317 0.85 CNR2 (0.45) CNR2CNR1
SCHEMBL25123338 0.81 PPARA (0.55) CNR2CNR1
SCHEMBL25123363 0.77 FFAR1 (0.44) CNR2CNR1
SCHEMBL24029374 0.76 CNR2 (0.47) CNR2CNR1
SCHEMBL25122727 0.76 PPARG (0.40) CYP4F2CYP4A11
SCHEMBL24847860 0.75 MTNR1A (0.33) CNR2CNR1CYP4F2CYP4A11
SCHEMBL29307145 0.75 CNR1 (0.47) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11746120-B2 Stat degraders and uses thereof KYMERA THERAPEUTICS, INC. (US) 2023-09-05 — — US disclosed
US-20230110180-A1 CDK2 DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2023-04-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11746120-B2 Stat degraders and uses thereof STAT4, STAT1, STAT3 CNR2 2461/4885CNR1 2602/4885CYP4F2 769/4885
US-20230110180-A1 CDK2 DEGRADERS AND USES THEREOF CDK2, CDK20, CDK1 CNR2 2940/4885CNR1 2779/4885CYP4F2 2249/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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