Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.53 |
| ▸ | BAD | Q92934 | 1/20 | 0.53 |
| ▸ | CTSL | P07711 | 2/20 | 0.52 |
| ▸ | CTSK | P43235 | 1/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALPG | P10696 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.49 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17950520 | 0.92 | ATM (0.75) | ATMTDP1L3MBTL1SRD5A2CTSL | |
| SCHEMBL209624 | 0.92 | ATM (0.67) | ATMTDP1L3MBTL1SRD5A2CTSL | |
| SCHEMBL110317 | 0.88 | SRD5A2 (0.74) | ATMTDP1L3MBTL1SRD5A2CA1 | |
| SCHEMBL13297330 | 0.86 | ATM (0.59) | ATMTDP1L3MBTL1CA1CA2 | |
| SCHEMBL9727858 | 0.86 | SRD5A2 (0.78) | ATMTDP1L3MBTL1SRD5A2CA1 | |
| SCHEMBL30320253 | 0.86 | ATM (0.86) | ATMTDP1L3MBTL1SRD5A2CA1 | |
| SCHEMBL141056 | 0.86 | ATM (0.86) | ATMTDP1L3MBTL1SRD5A2CA1 | |
| SCHEMBL2405473 | 0.86 | SRD5A2 (0.77) | ATMTDP1L3MBTL1SRD5A2CA1 | |
| SCHEMBL766131 | 0.85 | ATM (0.76) | ATMTDP1L3MBTL1SRD5A2CA1 | |
| SCHEMBL3038873 | 0.84 | CES2 (0.63) | ATMTDP1L3MBTL1CTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110245088-A1 | AMIDE-BASED SOLUTION-PHASE DERIVED LIBRARY AND METHOD FOR SCREENING THEREOF | NATIONAL TSING HUA UNIVERSITY (TW) | 2011-10-06 | — | — | US | claimed |
| US-5663179-A | CAN SENSITIZE MULTIDRUG RESISTANT CANCER CELLS TO CHEMOTHERAPEUTIC AGENTS | LABORATOIRES GLAXO SA (FR) | 1997-09-02 | — | — | US | disclosed |
| EP-0649410-B1 | ANILIDE DERIVATIVES | GLAXO LAB SA (FR) | 1997-05-02 | — | — | EP | disclosed |
| EP-0649410-A1 | ANILIDE DERIVATIVES. | GLAXO LAB SA (FR) | 1995-04-26 | — | — | EP | disclosed |
| WO-1994001408-A1 | ANILIDE DERIVATIVES | LABORATOIRES GLAXO S.A. (FR) | 1994-01-20 | — | — | WO | disclosed |