Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | ABL1 | P00519 | 2/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | BCR | P11274 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
| ▸ | PRKCA | P17252 | 1/20 | 0.47 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21646511 | 0.83 | IDO1 (0.58) | IDO1CYP3A4ABL1PDGFRBBCR | |
| SCHEMBL1798849 | 0.82 | CYP3A4 (0.55) | CYP3A4CYP19A1CYP11B1CYP11B2CYP2A6 | |
| SCHEMBL21362368 | 0.78 | CYP3A4 (0.62) | IDO1CYP3A4ABL1PDGFRBBCR | |
| SCHEMBL14489499 | 0.78 | IDO1 (0.75) | IDO1CYP3A4CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL4475935 | 0.77 | IDO1 (0.55) | IDO1CYP3A4CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL8592858 | 0.77 | ABL1 (0.67) | IDO1CYP3A4ABL1PDGFRBBCR | |
| SCHEMBL12017933 | 0.77 | CYP3A4 (0.60) | IDO1CYP3A4ABL1PDGFRBBCR | |
| SCHEMBL2643843 | 0.77 | IDO1 (0.55) | IDO1CYP3A4ABL1PDGFRBBCR | |
| SCHEMBL4485099 | 0.76 | IDO1 (0.58) | IDO1CYP3A4CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL8214338 | 0.76 | TAAR1 (0.55) | IDO1CYP3A4ABL1PDGFRBBCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230109839-A1 | THERAPEUTIC AGENT FOR TAUOPATHIES | Sumitomo Pharma Co., Ltd. (JP) | 2023-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230109839-A1 | THERAPEUTIC AGENT FOR TAUOPATHIES | MAPT, PSEN1, PSEN2 | IDO1 4698/4885CYP3A4 4734/4885ABL1 3883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.