SCHEMBL25124757

SCHEMBL25124757

Clc1ccc(-c2ccccc2-c2ccccc2-c2cccc3cccc(-c4ccccc4)c23)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.56
TSHR P16473 2/20 0.56
MAPK1 P28482 2/20 0.56
HSD17B10 Q99714 2/20 0.56
L3MBTL1 Q9Y468 2/20 0.56
ATM Q13315 1/20 0.56
CYP1A2 P05177 1/20 0.50
CASP1 P29466 2/20 0.46
CASP7 P55210 2/20 0.46
CYP3A4 P08684 2/20 0.46
PABPC1 P11940 1/20 0.46
DNMT1 P26358 1/20 0.46
HPGD P15428 2/20 0.45
TP53 P04637 1/20 0.45
HIF1A Q16665 1/20 0.45
PTGS2 P35354 2/20 0.43
PTGS1 P23219 1/20 0.43
KDM4E B2RXH2 3/20 0.43
LMNA P02545 1/20 0.43
GAA P10253 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25125411 1.00 ALDH1A1 (0.56) ALDH1A1TSHRMAPK1HSD17B10L3MBTL1
SCHEMBL24725941 0.94 CYP1A2 (0.56) ALDH1A1TSHRMAPK1HSD17B10L3MBTL1
SCHEMBL25125407 0.92 CYP1A2 (0.60) ALDH1A1TSHRMAPK1HSD17B10L3MBTL1
SCHEMBL25809996 0.88 ALDH1A1 (0.50) ALDH1A1TSHRMAPK1HSD17B10L3MBTL1
SCHEMBL25125271 0.87 ALDH1A1 (0.46) ALDH1A1TSHRMAPK1HSD17B10L3MBTL1
SCHEMBL25125276 0.86 ALDH1A1 (0.48) ALDH1A1TSHRMAPK1HSD17B10L3MBTL1
Fluoranthene SCHEMBL3078855 0.86 ALDH1A1 (0.75) ALDH1A1TSHRMAPK1HSD17B10L3MBTL1
SCHEMBL25125124 0.86 CYP1A2 (0.52) ALDH1A1TSHRMAPK1HSD17B10L3MBTL1
SCHEMBL25124897 0.86 ALDH1A1 (0.52) ALDH1A1TSHRMAPK1HSD17B10L3MBTL1
SCHEMBL24901117 0.86 MAPK1 (0.52) ALDH1A1TSHRMAPK1HSD17B10L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11711973-B2 Organic electronic device DUK SAN NEOLUX CO., LTD. (KR) 2023-07-25 US disclosed
US-11711973-B2 Organic electronic device DUK SAN NEOLUX CO., LTD. (KR) 2023-07-25 US disclosed
US-20230111469-A1 Organic Electronic Device DUK SAN NEOLUX CO., LTD. (KR) 2023-04-13 US disclosed