Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.53 |
| ▸ | SYK | P43405 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | KLK7 | P49862 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 2/20 | 0.47 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
| ▸ | CTSK | P43235 | 2/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25129695 | 1.00 | KLK5 (0.53) | KLK5SYKPPARAKLK7CTSS | |
| SCHEMBL12873000 | 0.91 | KLK5 (0.57) | KLK5SYKPPARACTSSCTSL | |
| SCHEMBL6388701 | 0.91 | KLK5 (0.57) | KLK5SYKPPARACTSSCTSL | |
| SCHEMBL12214464 | 0.91 | KLK5 (0.57) | KLK5SYKPPARACTSSCTSL | |
| SCHEMBL8141342 | 0.87 | CTSK (0.56) | KLK5SYKCTSSCTSBCTSK | |
| SCHEMBL5311477 | 0.87 | SYK (0.52) | KLK5SYKPPARAKLK7CTSS | |
| SCHEMBL21684844 | 0.87 | CTSK (0.56) | KLK5SYKCTSSCTSBCTSK | |
| SCHEMBL6279109 | 0.87 | CTSK (0.56) | KLK5SYKCTSSCTSBCTSK | |
| SCHEMBL28870542 | 0.86 | KLK5 (0.52) | KLK5SYKPPARAKLK7CTSS | |
| SCHEMBL3740512 | 0.86 | KLK5 (0.52) | KLK5SYKPPARAKLK7CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118354796-A | Compounds, pharmaceutical compositions and methods for treating, preventing or managing hyperproliferative disorders | 文赛克斯制药有限责任公司 | 2024-07-16 | — | — | CN | disclosed |
| WO-2023057814-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS FOR THE TREATMENT, PREVENTION, OR MANAGEMENT OF HYPERPROLIFERATIVE DISORDERS | VINCERX PHARMA GMBH (DE) | 2023-04-13 | — | — | WO | disclosed |