Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD38 | P28907 | 20/20 | 0.84 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.81 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.81 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25135802 | 1.00 | CD38 (0.84) | CD38CYP2D6CYP2B6CYP2C19 | |
| SCHEMBL25135803 | 0.91 | CD38 (1.00) | CD38CYP2D6CYP2B6CYP2C19 | |
| SCHEMBL25135990 | 0.91 | CD38 (1.00) | CD38CYP2D6CYP2B6CYP2C19 | |
| SCHEMBL25135859 | 0.90 | CD38 (1.00) | CD38CYP2D6CYP2B6CYP2C19 | |
| SCHEMBL25136022 | 0.90 | CD38 (1.00) | CD38CYP2D6CYP2B6CYP2C19 | |
| SCHEMBL25136138 | 0.86 | CD38 (1.00) | CD38CYP2D6CYP2B6CYP2C19 | |
| SCHEMBL29182237 | 0.86 | CD38 (1.00) | CD38CYP2D6CYP2B6CYP2C19 | |
| SCHEMBL30040406 | 0.86 | CD38 (1.00) | CD38CYP2D6CYP2B6CYP2C19 | |
| SCHEMBL25135870 | 0.85 | CD38 (0.83) | CD38CYP2D6CYP2B6CYP2C19 | |
| SCHEMBL25135925 | 0.85 | CD38 (0.83) | CD38CYP2D6CYP2B6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230158024-A1 | CD38 INHIBITORS | Astellas Engineered Small Molecules US, Incorporated | 2023-05-25 | — | — | US | disclosed |
| US-20230116972-A1 | CD38 MODULATORS AND METHODS OF USE THEREOF | CYTOKINETICS, INC. | 2023-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230116972-A1 | CD38 MODULATORS AND METHODS OF USE THEREOF | CD38, CXCR4, FCGRT | CD38 1/4885CYP2D6 1605/4885CYP2B6 2184/4885 |
| US-20230158024-A1 | CD38 INHIBITORS | CD38, NQO1, NDUFAB1 | CD38 1/4885CYP2D6 1675/4885CYP2B6 3067/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.