Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD38 | P28907 | 3/20 | 0.41 |
| ▸ | CNR2 | P34972 | 4/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 2/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25136114 | 0.88 | CD38 (0.44) | CD38CYP2D6CYP2B6CYP3A4IDO1 | |
| SCHEMBL30363781 | 0.88 | CD38 (0.44) | CD38CYP2D6CYP2B6CYP3A4IDO1 | |
| SCHEMBL29182198 | 0.88 | CD38 (0.44) | CD38CYP2D6CYP2B6CYP3A4IDO1 | |
| SCHEMBL30363585 | 0.86 | S1PR2 (0.38) | CD38CYP2D6CYP2B6CYP3A4IDO1 | |
| SCHEMBL25136172 | 0.86 | S1PR2 (0.38) | CD38CYP2D6CYP2B6CYP3A4IDO1 | |
| SCHEMBL25136093 | 0.84 | CD38 (0.45) | CD38CYP2D6CYP2B6CYP3A4IDO1 | |
| SCHEMBL30363917 | 0.84 | CD38 (0.45) | CD38CYP2D6CYP2B6CYP3A4IDO1 | |
| SCHEMBL29182246 | 0.84 | CD38 (0.45) | CD38CYP2D6CYP2B6CYP3A4IDO1 | |
| SCHEMBL25136036 | 0.83 | CD38 (0.43) | CD38CYP2D6CYP2B6CYP3A4IDO1 | |
| SCHEMBL29182177 | 0.83 | CD38 (0.43) | CD38CYP2D6CYP2B6CYP3A4IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230116972-A1 | CD38 MODULATORS AND METHODS OF USE THEREOF | CYTOKINETICS, INC. | 2023-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230116972-A1 | CD38 MODULATORS AND METHODS OF USE THEREOF | CD38, CXCR4, FCGRT | CD38 1/4885CNR2 547/4885HSD11B1 496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.