Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CD38 | P28907 | 3/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 3/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.34 |
| ▸ | WNT1 | P04628 | 2/20 | 0.34 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30363585 | 1.00 | S1PR2 (0.38) | S1PR2SMYD3NPC1RAB9ATSHR | |
| SCHEMBL30363781 | 0.88 | CD38 (0.44) | SMYD3NPC1RAB9ATSHRSMN1; SMN2 | |
| SCHEMBL29182198 | 0.88 | CD38 (0.44) | SMYD3NPC1RAB9ATSHRSMN1; SMN2 | |
| SCHEMBL25136114 | 0.88 | CD38 (0.44) | SMYD3NPC1RAB9ATSHRSMN1; SMN2 | |
| SCHEMBL25136247 | 0.86 | CD38 (0.41) | CD38CYP3A4CYP2D6IDO1CYP2B6 | |
| SCHEMBL25136297 | 0.86 | ALDH1A1 (0.40) | S1PR2SMYD3NPC1RAB9ATSHR | |
| SCHEMBL29182201 | 0.86 | ALDH1A1 (0.40) | S1PR2SMYD3NPC1RAB9ATSHR | |
| SCHEMBL25136188 | 0.86 | ALDH1A1 (0.40) | S1PR2SMYD3NPC1RAB9ATSHR | |
| SCHEMBL25136474 | 0.84 | CD38 (0.50) | S1PR2CD38CYP2D6CYP2B6GSK3B | |
| SCHEMBL30363631 | 0.84 | CD38 (0.50) | S1PR2CD38CYP2D6CYP2B6GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230116972-A1 | CD38 MODULATORS AND METHODS OF USE THEREOF | CYTOKINETICS, INC. | 2023-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230116972-A1 | CD38 MODULATORS AND METHODS OF USE THEREOF | CD38, CXCR4, FCGRT | S1PR2 412/4885SMYD3 2117/4885NPC1 2619/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.