⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24174696 | 0.77 | — | — | |
| SCHEMBL30415941 | 0.77 | — | — | |
| SCHEMBL24174525 | 0.74 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL31287333 | 0.71 | — | — | |
| SCHEMBL31258769 | 0.71 | — | — | |
| SCHEMBL31368721 | 0.69 | KHK (0.44) | — | |
| SCHEMBL31258708 | 0.69 | KHK (0.37) | — | |
| SCHEMBL31368716 | 0.69 | CYP1A2 (0.36) | — | |
| SCHEMBL31368717 | 0.69 | CYP1A2 (0.36) | — | |
| SCHEMBL23930268 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4735438-A2 | HETEROBIFUNCTIONAL COMPOUNDS FOR THE DEGRADATION OF KRAS | Merck Patent GmbH (DE) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025006783-A2 | HETEROBIFUNCTIONAL COMPOUNDS FOR THE DEGRADATION OF KRAS | MERCK PATENT GMBH (DE) | 2025-01-02 | — | — | WO | disclosed |
| WO-2023061463-A1 | NOVEL PYRIMIDOPYRIDINE COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | 广东东阳光药业有限公司 | 2023-04-20 | — | — | WO | disclosed |