⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30415941 | 1.00 | — | — | |
| SCHEMBL23152571 | 0.81 | — | — | |
| SCHEMBL23673410 | 0.77 | ALDH1A1 (0.32) | — | |
| SCHEMBL30599213 | 0.77 | ALDH1A1 (0.32) | — | |
| SCHEMBL25136990 | 0.77 | — | — | |
| SCHEMBL24174525 | 0.77 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL31258769 | 0.74 | — | — | |
| SCHEMBL31258708 | 0.73 | KHK (0.37) | — | |
| SCHEMBL18260463 | 0.71 | TDP1 (0.44) | — | |
| SCHEMBL19356946 | 0.71 | ALDH1A1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024182551-A1 | LZK INHIBITORS | UEREKA BIOSCIENCES, INC. (US) | 2024-09-06 | — | — | WO | disclosed |
| US-20230339927-A1 | ATR INHIBITORS AND USES THEREOF | ANTENGENE DISCOVERY LIMITED (CN) | 2023-10-26 | — | — | US | disclosed |
| US-20230339927-A1 | ATR INHIBITORS AND USES THEREOF | ANTENGENE DISCOVERY LIMITED (CN) | 2023-10-26 | — | — | US | disclosed |
| CN-116134022-A | ATR inhibitors and uses thereof | 上海德琪医药科技有限公司 | 2023-05-16 | — | — | CN | disclosed |
| WO-2022002245-A1 | ATR INHIBITORS AND USES THEREOF | SHANGHAI ANTENGENE CORPORATION LIMITED (CN) | 2022-01-06 | — | — | WO | disclosed |