SCHEMBL2513736

SCHEMBL2513736

CCCCc1ccc(-c2cccc3c2C=C(C(C)C)C3[Zr](Cl)(Cl)(C2C(C(C)C)=Cc3c(-c4ccc(CCCC)cc4)cccc32)[SiH](C)C)cc1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
RARB P10826 1/20 0.32
BRS3 P32247 1/20 0.31
HSD11B1 P28845 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2512516 0.97 HSD11B1 (0.34) RARBHSD11B1
SCHEMBL2513821 0.96 RARB (0.34) RARBHSD11B1
SCHEMBL2512475 0.94
SCHEMBL4323895 0.89
SCHEMBL2516263 0.89 EDNRB (0.31)
SCHEMBL2508943 0.87 RARB (0.34) RARBBRS3HSD11B1
SCHEMBL5351724 0.86 RARB (0.33) RARBBRS3HSD11B1
SCHEMBL5354174 0.86 HSD11B1 (0.34) RARBBRS3HSD11B1
SCHEMBL2514626 0.86 RARB (0.33) RARBBRS3HSD11B1
SCHEMBL5954203 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8034886-B2 Process for manufacturing high to ultra high molecular weight polymers using novel bridged metallocene catalysts TICONA GMBH (DE) 2011-10-11 US disclosed
US-20100056737-A1 Process for manufacturing high to ultra high molecular weight polymers using novel bridged metallocene catalysts NUTRINOVA NUTRITION SPECIALTIES & FOOD INGREDIENTS GMBH (DE) 2010-03-04 US disclosed
US-7598329-B2 Process for manufacturing ultra high molecular weight polymers using novel bridged metallocene catalysts TICONA GMBH (DE) 2009-10-06 US disclosed
US-20070105712-A1 Process for manufacturing ultra high molecular weight polymers using novel bridged metallocene catalysts NUTRINOVA NUTRITION SPECIALTIES & FOOD INGREDIENTS GMBH (DE) 2007-05-10 US disclosed