Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 8/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23898766 | 0.86 | TSHR (0.44) | TSHRTHRBCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL24937950 | 0.84 | THRB (0.38) | TSHRTHRBCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL13010231 | 0.83 | TSHR (0.37) | TSHRTHRBSMN1; SMN2HTTLMNA | |
| SCHEMBL13010228 | 0.81 | TSHR (0.38) | TSHRTHRBSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL18649978 | 0.81 | SMN1; SMN2 (0.47) | TSHRTHRBCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL18094748 | 0.81 | TSHR (0.47) | TSHRTHRBCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL2731965 | 0.80 | THRB (0.44) | TSHRTHRBCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL22546485 | 0.79 | TSHR (0.41) | TSHRTHRBCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL21255713 | 0.79 | TSHR (0.43) | TSHRTHRBCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL21255712 | 0.79 | THRB (0.45) | TSHRTHRBACHESMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230123608-A1 | OPTICAL ELEMENT, LIGHT GUIDE ELEMENT, AND LIQUID CRYSTAL COMPOSITION | FUJIFILM CORPORATION (JP) | 2023-04-20 | — | — | US | disclosed |