Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23319851 | 0.88 | NLRP3 (0.36) | ALDH1A1GLANLRP3TRPA1KDM4E | |
| SCHEMBL20699030 | 0.88 | NLRP3 (0.36) | ALDH1A1GLANLRP3TRPA1MTNR1A | |
| SCHEMBL20699031 | 0.86 | NLRP3 (0.34) | NLRP3 | |
| SCHEMBL25139131 | 0.85 | NLRP3 (0.34) | NLRP3 | |
| SCHEMBL20698785 | 0.82 | NLRP3 (0.48) | ALDH1A1GLANLRP3TRPA1KDM4E | |
| SCHEMBL23319819 | 0.80 | NLRP3 (0.37) | ALDH1A1GLANLRP3TRPA1KDM4E | |
| SCHEMBL24116478 | 0.79 | NLRP3 (0.43) | ALDH1A1GLANLRP3TRPA1KDM4E | |
| SCHEMBL29691414 | 0.75 | AAK1 (0.41) | ALDH1A1GLANLRP3TRPA1RET | |
| SCHEMBL23012442 | 0.75 | AAK1 (0.41) | ALDH1A1GLANLRP3TRPA1RET | |
| SCHEMBL20698952 | 0.74 | NLRP3 (0.35) | NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3658538-B1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS AG (CH) | 2023-04-19 | — | — | EP | disclosed |