Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 15/20 | 0.63 |
| ▸ | INSR | P06213 | 6/20 | 0.63 |
| ▸ | EGFR | P00533 | 6/20 | 0.63 |
| ▸ | IGF1R | P08069 | 5/20 | 0.63 |
| ▸ | BTK | Q06187 | 3/20 | 0.63 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.63 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.63 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.63 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.63 |
| ▸ | BMPR1B | O00238 | 2/20 | 0.63 |
| ▸ | PLK4 | O00444 | 2/20 | 0.63 |
| ▸ | GAK | O14976 | 2/20 | 0.63 |
| ▸ | ERN1 | O75460 | 2/20 | 0.63 |
| ▸ | STK10 | O94804 | 2/20 | 0.63 |
| ▸ | ABL1 | P00519 | 2/20 | 0.63 |
| ▸ | LCK | P06239 | 2/20 | 0.63 |
| ▸ | FYN | P06241 | 2/20 | 0.63 |
| ▸ | FES | P07332 | 2/20 | 0.63 |
| ▸ | YES1 | P07947 | 2/20 | 0.63 |
| ▸ | HCK | P08631 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30044572 | 1.00 | ALK (0.63) | ALKINSREGFRIGF1RBTK | |
| SCHEMBL25139831 | 0.89 | ALK (0.60) | ALKINSREGFRIGF1RBTK | |
| SCHEMBL30044417 | 0.89 | ALK (0.60) | ALKINSREGFRIGF1RBTK | |
| SCHEMBL30044020 | 0.88 | INSR (0.54) | ALKINSREGFRIGF1RBTK | |
| SCHEMBL25139876 | 0.88 | INSR (0.54) | ALKINSREGFRIGF1RBTK | |
| SCHEMBL25139880 | 0.88 | ALK (0.54) | ALKINSREGFRIGF1RBTK | |
| SCHEMBL30045121 | 0.86 | ALK (0.56) | ALKINSREGFRIGF1RBTK | |
| SCHEMBL25139826 | 0.86 | ALK (0.56) | ALKINSREGFRIGF1RBTK | |
| SCHEMBL25139832 | 0.84 | PLK1 (0.55) | ALKINSREGFRIGF1RBTK | |
| SCHEMBL30044170 | 0.84 | PLK1 (0.55) | ALKINSREGFRIGF1RBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230125046-A1 | CYANO-SUBSTITUTED PYRIDINE AND CYANO-SUBSTITUTED PYRIMIDINE COMPOUND AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | BEIJING SCITECH-MQ PHARMACEUTICALS LIMITED (CN) | 2023-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230125046-A1 | CYANO-SUBSTITUTED PYRIDINE AND CYANO-SUBSTITUTED PYRIMIDINE COMPOUND AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | FGFR4, FGFR1, WEE1 | ALK 149/4885INSR 683/4885EGFR 561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.