Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 12/20 | 0.44 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25143066 | 0.90 | NPC1 (0.50) | NPC1RAB9AMEN1KMT2ARXFP1 | |
| SCHEMBL24072476 | 0.90 | MAPT (0.43) | NPC1RAB9ACYP3A4HDAC3HDAC1 | |
| SCHEMBL25142563 | 0.89 | RAB9A (0.47) | NPC1RAB9AMEN1KMT2ARXFP1 | |
| SCHEMBL30142692 | 0.88 | CYP3A4 (0.41) | CYP3A4HDAC3HDAC1SMN1; SMN2HDAC2 | |
| SCHEMBL25143314 | 0.87 | RAB9A (0.53) | NPC1RAB9AMEN1KMT2ARXFP1 | |
| SCHEMBL25143465 | 0.87 | RAB9A (0.53) | NPC1RAB9AMEN1KMT2ARXFP1 | |
| SCHEMBL31665594 | 0.85 | RAB9A (0.55) | NPC1RAB9AMEN1KMT2ARXFP1 | |
| SCHEMBL25143086 | 0.83 | RAB9A (0.55) | NPC1RAB9AMEN1KMT2ARXFP1 | |
| SCHEMBL25143490 | 0.83 | RAB9A (0.57) | NPC1RAB9AMEN1KMT2ARXFP1 | |
| SCHEMBL25143063 | 0.83 | RAB9A (0.57) | NPC1RAB9AMEN1KMT2ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023061440-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | CULLGEN (SHANGHAI), INC. (CN) | 2023-04-20 | — | — | WO | disclosed |