SCHEMBL25145265

SCHEMBL25145265

CCCCCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)NC(C)C(C)C

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 8/20 0.48
FAAH O00519 5/20 0.46
MEN1 O00255 1/20 0.46
MAPK1 P28482 1/20 0.46
KMT2A Q03164 1/20 0.46
LPAR1 Q92633 2/20 0.42
LPAR2 Q9HBW0 2/20 0.42
ENPP2 Q13822 1/20 0.42
DNM1 Q05193 2/20 0.42
ASAH2 Q9NR71 1/20 0.42
ALDH1A1 P00352 1/20 0.41
ASAH1 Q13510 1/20 0.41
ACER2 Q5QJU3 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25067300 0.85 FAAH (0.59) GLP1RFAAHLPAR1LPAR2ENPP2
SCHEMBL25145260 0.85 GLP1R (0.41) GLP1RFAAHMEN1MAPK1KMT2A
SCHEMBL14801865 0.84 FAAH (0.58) GLP1RFAAHMEN1MAPK1KMT2A
SCHEMBL14801378 0.84 FAAH (0.58) GLP1RFAAHMEN1MAPK1KMT2A
SCHEMBL14801268 0.84 FAAH (0.58) GLP1RFAAHMEN1MAPK1KMT2A
SCHEMBL14801845 0.84 FAAH (0.58) GLP1RFAAHMEN1MAPK1KMT2A
SCHEMBL7646590 0.82 FAAH (0.62) GLP1RFAAHLPAR1LPAR2ENPP2
SCHEMBL13811075 0.82 FAAH (0.62) GLP1RFAAHLPAR1LPAR2ENPP2
SCHEMBL7647954 0.82 FAAH (0.62) GLP1RFAAHLPAR1LPAR2ENPP2
SCHEMBL7650140 0.82 FAAH (0.62) GLP1RFAAHLPAR1LPAR2ENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3838893-B1 LINKER, ANTIBODY-DRUG CONJUGATE INCLUDING SAME, AND USE THEREOF ACAD OF MILITARY MEDICAL SCIENCES (CN) 2023-04-19 EP disclosed