Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.46 |
| ▸ | PIM1 | P11309 | 2/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 5/20 | 0.40 |
| ▸ | HTR2A | P28223 | 4/20 | 0.40 |
| ▸ | HTR2B | P41595 | 4/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5763019 | 0.87 | ADRB1 (0.45) | ADRB1CACNA1HPIM1SYKHTR2C | |
| SCHEMBL31239629 | 0.79 | ADRB1 (0.39) | ADRB1CACNA1HSYKHTR2CHTR2A | |
| Hydrochloric Acid SCHEMBL6152965 | 0.75 | HRH4 (0.54) | ADRB1PIM1SYKBRD4HRH4 | |
| SCHEMBL25145914 | 0.73 | MALT1 (0.43) | ADRB1CACNA1HPIM1HTR2CCACNA1G | |
| SCHEMBL5688150 | 0.73 | GBA1 (0.52) | CACNA1HGBA1KCNH2HRH4HRH3 | |
| SCHEMBL25145546 | 0.72 | CACNA1H (0.47) | CACNA1HHTR2CHTR2BCACNA1GGBA1 | |
| SCHEMBL25145959 | 0.72 | GBA1 (0.47) | CACNA1HCACNA1GGBA1PIK3CAKCNH2 | |
| SCHEMBL2243533 | 0.71 | MAPK1 (0.55) | ADRB1SYKMAPK1PIK3CAKCNH2 | |
| SCHEMBL25145644 | 0.71 | MAPK1 (0.55) | ADRB1CACNA1HHTR2CHTR2BCACNA1G | |
| SCHEMBL940757 | 0.71 | SYK (0.51) | ADRB1SYKHTR2CHTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023062049-A1 | HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-04-20 | — | — | WO | disclosed |