Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 4/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | OGT | O15294 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25146120 | 0.92 | MGLL (0.36) | MGLLKCNH2HRH3LMNASMN1; SMN2 | |
| SCHEMBL25145728 | 0.92 | MGLL (0.36) | MGLLKCNH2HRH3LMNASMN1; SMN2 | |
| SCHEMBL30409400 | 0.90 | MGLL (0.34) | MGLL | |
| SCHEMBL25146114 | 0.90 | MGLL (0.37) | MGLLKCNH2HRH3OGTCYP2C9 | |
| SCHEMBL25145940 | 0.89 | MGLL (0.33) | MGLL | |
| SCHEMBL25145936 | 0.89 | MGLL (0.33) | MGLL | |
| SCHEMBL25145655 | 0.88 | MGLL (0.39) | MGLLKCNH2HRH3CYP2C9CYP2C19 | |
| SCHEMBL25145599 | 0.88 | KCNH2 (0.38) | MGLLKCNH2HRH3LMNASMN1; SMN2 | |
| SCHEMBL25145657 | 0.88 | MGLL (0.35) | MGLLKCNH2HRH3GRIN2DGRIN3B | |
| SCHEMBL25146156 | 0.87 | MGLL (0.49) | MGLLKCNH2HRH3LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023062049-A1 | HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-04-20 | — | — | WO | disclosed |