⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23467560 | 0.87 | HRH3 (0.31) | — | |
| SCHEMBL19099924 | 0.82 | — | — | |
| SCHEMBL18648859 | 0.81 | HRH3 (0.33) | — | |
| SCHEMBL18697407 | 0.78 | — | — | |
| SCHEMBL22837865 | 0.76 | — | — | |
| SCHEMBL24022579 | 0.75 | HRH3 (0.38) | — | |
| SCHEMBL22903962 | 0.75 | CCR2 (0.30) | — | |
| SCHEMBL23513066 | 0.75 | — | — | |
| SCHEMBL21993492 | 0.75 | — | — | |
| SCHEMBL18633843 | 0.75 | HRH3 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230117631-A1 | HPK1 ANTAGONISTS AND USES THEREOF | Nimbus Saturn, Inc. | 2023-04-20 | — | — | US | disclosed |