Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.56 |
| ▸ | S1PR1 | P21453 | 14/20 | 0.56 |
| ▸ | CDKN1A | P38936 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CASP6 | P55212 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30762323 | 1.00 | SIRT1 (0.60) | SIRT1RECQLSIRT2S1PR1CDKN1A | |
| SCHEMBL30762321 | 1.00 | SIRT1 (0.60) | SIRT1RECQLSIRT2S1PR1CDKN1A | |
| SCHEMBL29141442 | 1.00 | SIRT1 (0.60) | SIRT1RECQLSIRT2S1PR1CDKN1A | |
| SCHEMBL2297254 | 0.86 | S1PR1 (0.60) | SIRT1S1PR1 | |
| SCHEMBL30762322 | 0.86 | S1PR1 (0.60) | SIRT1S1PR1 | |
| SCHEMBL29141420 | 0.86 | S1PR1 (0.60) | SIRT1S1PR1 | |
| SCHEMBL32666146 | 0.86 | S1PR1 (0.60) | SIRT1S1PR1 | |
| SCHEMBL25147645 | 0.85 | SIRT1 (0.56) | SIRT1RECQLSIRT2S1PR1CDKN1A | |
| SCHEMBL5421567 | 0.85 | S1PR1 (0.59) | S1PR1 | |
| SCHEMBL5088953 | 0.85 | S1PR1 (0.59) | S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117430547-A | Preparation method of single enantiomer of tetrahydrocyclopenta [ b ] indol-3-yl acetic acid and derivative thereof | 安徽艾立德制药有限公司 | 2024-01-23 | — | — | CN | disclosed |
| WO-2023064458-A1 | SELECTIVE JAK2 INHIBITORS AND METHODS OF USE | YALE UNIVERSITY (US) | 2023-04-20 | — | — | WO | disclosed |