Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.37 |
| ▸ | RARB | P10826 | 4/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.32 |
| ▸ | BRS3 | P32247 | 2/20 | 0.32 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.32 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2517328 | 0.96 | HSD11B1 (0.37) | HSD11B1RARB | |
| SCHEMBL2513849 | 0.94 | KCNH2 (0.31) | — | |
| SCHEMBL2511754 | 0.90 | EDNRB (0.35) | — | |
| SCHEMBL2508943 | 0.87 | RARB (0.34) | HSD11B1RARBBRS3 | |
| SCHEMBL2508944 | 0.87 | — | — | |
| SCHEMBL5891062 | 0.86 | — | — | |
| SCHEMBL5354174 | 0.86 | HSD11B1 (0.34) | HSD11B1RARBPSMB5BRS3 | |
| SCHEMBL2514626 | 0.86 | RARB (0.33) | HSD11B1RARBBRS3 | |
| SCHEMBL5351724 | 0.86 | RARB (0.33) | HSD11B1RARBBRS3 | |
| SCHEMBL139314 | 0.85 | BCHE (0.31) | PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8034886-B2 | Process for manufacturing high to ultra high molecular weight polymers using novel bridged metallocene catalysts | TICONA GMBH (DE) | 2011-10-11 | — | — | US | disclosed |
| US-20100056737-A1 | Process for manufacturing high to ultra high molecular weight polymers using novel bridged metallocene catalysts | NUTRINOVA NUTRITION SPECIALTIES & FOOD INGREDIENTS GMBH (DE) | 2010-03-04 | — | — | US | disclosed |
| US-7598329-B2 | Process for manufacturing ultra high molecular weight polymers using novel bridged metallocene catalysts | TICONA GMBH (DE) | 2009-10-06 | — | — | US | disclosed |
| US-20070105712-A1 | Process for manufacturing ultra high molecular weight polymers using novel bridged metallocene catalysts | NUTRINOVA NUTRITION SPECIALTIES & FOOD INGREDIENTS GMBH (DE) | 2007-05-10 | — | — | US | disclosed |