Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 7/20 | 0.49 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NNMT | P40261 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.40 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | AKT2 | P31751 | 1/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.39 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30399843 | 0.88 | MKNK1 (0.45) | FYNMKNK1MKNK2ATMTGFBR1 | |
| SCHEMBL25148814 | 0.81 | CHEK1 (0.46) | FYNMKNK1MKNK2ATMTGFBR1 | |
| SCHEMBL3490519 | 0.81 | FYN (0.55) | FYNATMRIPK2KDM4ENPC1 | |
| SCHEMBL25149706 | 0.80 | MKNK1 (0.44) | FYNMKNK1MKNK2HCAR3ATM | |
| SCHEMBL3299202 | 0.80 | ALDH1A1 (0.63) | HCAR3NNMTKDM4ENPC1ALDH1A1 | |
| Lithium Ion SCHEMBL30400130 | 0.78 | MKNK1 (0.42) | FYNMKNK1MKNK2ATMTGFBR1 | |
| SCHEMBL25149584 | 0.78 | MKNK1 (0.44) | FYNMKNK1MKNK2ATMTGFBR1 | |
| SCHEMBL31141821 | 0.78 | FYN (0.44) | FYNMKNK1MKNK2ATMTGFBR1 | |
| SCHEMBL31403956 | 0.77 | PIK3CD (0.44) | FYNMKNK1MKNK2ATMTGFBR1 | |
| SCHEMBL3850100 | 0.77 | PIK3CA (0.53) | FYNMKNK1MKNK2ATMTGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023061838-A1 | IMIDAZO[1,2-A]PYRIDINE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2023-04-20 | — | — | WO | disclosed |