SCHEMBL2515071

SCHEMBL2515071

C/C(=C\C(=O)O)CC(=O)O.CC(=CC(=O)O)CC(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.50
TSHR P16473 1/20 0.50
ATM Q13315 1/20 0.48
LDHA P00338 1/20 0.42
SRR Q9GZT4 1/20 0.42
KDM1A O60341 1/20 0.37
ALOX15 P16050 1/20 0.36
HSD17B10 Q99714 1/20 0.36
FFAR3 O14843 2/20 0.33
LMNA P02545 1/20 0.33
SLC15A2 Q16348 1/20 0.33
RECQL P46063 1/20 0.33
KDM6B O15054 1/20 0.33
KDM5C P41229 1/20 0.33
EGLN1 Q9GZT9 1/20 0.33
PHF8 Q9UPP1 1/20 0.33
KDM2A Q9Y2K7 1/20 0.33
POLB P06746 1/20 0.32
CTH P32929 1/20 0.32
FNTA P49354 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27827 1.00 KDM4E (0.50) KDM4ETSHRATMLDHASRR
SCHEMBL27826 1.00 KDM4E (0.50) KDM4ETSHRATMLDHASRR
SCHEMBL10947572 1.00 KDM4E (0.50) KDM4ETSHRATMLDHASRR
SCHEMBL28568597 0.83 KDM4E (0.48) KDM4ETSHRATMKDM1AFFAR3
SCHEMBL15693960 0.83 LDHA (0.42) KDM4ETSHRATMLDHASRR
SCHEMBL17304412 0.81 KDM4E (0.46) KDM4ETSHRATMKDM1AFFAR3
SCHEMBL17304359 0.81 KDM4E (0.46) KDM4ETSHRATMKDM1AFFAR3
SCHEMBL25658325 0.81 POLB (0.50) KDM4ETSHRATMLDHASRR
SCHEMBL17304209 0.81 KDM4E (0.46) KDM4ETSHRATMKDM1AFFAR3
SCHEMBL17304211 0.81 KDM4E (0.46) KDM4ETSHRATMKDM1AFFAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8038954-B2 CSF with low platinum/palladium ratios BASF CORPORATION (US) 2011-10-18 US disclosed
US-20110243801-A1 Passivation-Free Coating Process for a CSF BASF CORPORATION (US) 2011-10-06 US disclosed