Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25150811 | 0.86 | KDM4E (0.34) | GRM4KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL17185036 | 0.80 | GRM4 (0.43) | GRM4MEN1POLBKMT2A | |
| SCHEMBL22747759 | 0.78 | GRM4 (0.40) | GRM4KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL25151923 | 0.75 | — | — | |
| SCHEMBL25151163 | 0.74 | TLR9 (0.36) | HTT | |
| SCHEMBL25152279 | 0.74 | HTT (0.33) | GRM4HTT | |
| SCHEMBL18284018 | 0.70 | CHRNA7 (0.39) | GRM4KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL25151435 | 0.70 | GRM4 (0.33) | GRM4 | |
| SCHEMBL25152657 | 0.67 | GRM4 (0.31) | GRM4 | |
| SCHEMBL30378324 | 0.66 | CRBN (0.52) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064880-A1 | COMPOUNDS AND METHODS FOR MODULATING NUCLEIC ACID SPLICING | REMIX THERAPEUTICS INC. (US) | 2023-04-20 | — | — | WO | disclosed |