Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | OGA | O60502 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | MPO | P05164 | 1/20 | 0.30 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1987497 | 0.86 | FFAR1 (0.49) | FFAR1USP30MPO | |
| SCHEMBL657486 | 0.85 | FFAR1 (0.44) | FFAR1 | |
| SCHEMBL28649940 | 0.84 | FFAR1 (0.46) | FFAR1USP30OGAMPO | |
| SCHEMBL9100609 | 0.84 | FFAR1 (0.43) | FFAR1OGAMPO | |
| Tert-Butanol SCHEMBL22532841 | 0.84 | FFAR1 (0.50) | FFAR1USP30OGA | |
| SCHEMBL2517121 | 0.84 | FFAR1 (0.47) | FFAR1MPO | |
| SCHEMBL2572488 | 0.84 | FFAR1 (0.47) | FFAR1MPO | |
| SCHEMBL28254657 | 0.83 | FFAR1 (0.44) | FFAR1USP30DGAT1 | |
| SCHEMBL2749177 | 0.82 | FFAR1 (0.46) | FFAR1MPO | |
| SCHEMBL17801242 | 0.82 | FFAR1 (0.46) | FFAR1MPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2379523-A1 | 4, 6-DISUBSTITUTED 2-AMINO-PYRIMIDINES AS HISTAMINE H4 RECEPTOR MODULATORS | Incyte Corporation (US) | 2011-10-26 | — | — | EP | disclosed |
| WO-2010075270-A1 | 4, 6-DISUBSTITUTED 2-AMINO-PYRIMIDINES AS HISTAMINE H4 RECEPTOR MODULATORS | INCYTE CORPORATION (US) | 2010-07-01 | — | — | WO | disclosed |