Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 3/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.31 |
| ▸ | CCNC | P24863 | 1/20 | 0.30 |
| ▸ | CDK8 | P49336 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1581816 | 0.91 | FFAR1 (0.41) | FFAR1USP30DGAT1DDB1CRBN | |
| SCHEMBL320828 | 0.84 | USP30 (0.52) | FFAR1USP30DDB1CRBNBACE1 | |
| SCHEMBL2515083 | 0.83 | FFAR1 (0.47) | FFAR1USP30DGAT1 | |
| SCHEMBL25810563 | 0.81 | FFAR1 (0.43) | FFAR1USP30DGAT1DDB1CRBN | |
| SCHEMBL320321 | 0.81 | FFAR1 (0.42) | FFAR1USP30DDB1CRBNACHE | |
| SCHEMBL658691 | 0.81 | FFAR1 (0.42) | FFAR1CDK8 | |
| SCHEMBL25238268 | 0.81 | USP30 (0.49) | FFAR1USP30DDB1CRBNCCNC | |
| SCHEMBL16876545 | 0.80 | FFAR1 (0.44) | FFAR1USP30DGAT1DDB1CRBN | |
| SCHEMBL2422527 | 0.80 | USP30 (0.55) | FFAR1USP30DDB1CRBNCCNC | |
| SCHEMBL2423601 | 0.80 | USP30 (0.55) | FFAR1USP30DDB1CRBNCCNC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104059054-B | Three-level cyclic amine ALK kinase inhibitor for treating cancer | 浙江导明医药科技有限公司 | 2018-11-20 | — | — | CN | disclosed |