Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.46 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 5/20 | 0.40 |
| ▸ | EGFR | P00533 | 3/20 | 0.39 |
| ▸ | ABL1 | P00519 | 2/20 | 0.39 |
| ▸ | ABL2 | P42684 | 2/20 | 0.39 |
| ▸ | TNF | P01375 | 3/20 | 0.38 |
| ▸ | LITAF | Q99732 | 3/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
| ▸ | CTSE | P14091 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25151026 | 0.95 | HCAR1 (0.45) | USP30HCAR1TNFLITAFPIK3CA | |
| SCHEMBL25150914 | 0.89 | USP30 (0.47) | USP30HCAR1SRCEGFRABL1 | |
| SCHEMBL25151102 | 0.84 | HCAR1 (0.45) | USP30HCAR1CTSDCTSEBACE1 | |
| SCHEMBL25150870 | 0.83 | HCAR1 (0.44) | USP30HCAR1SRCEGFRABL1 | |
| SCHEMBL30186853 | 0.79 | USP30 (0.49) | USP30HCAR1CTSDCTSEBACE1 | |
| SCHEMBL25151023 | 0.78 | HCAR1 (0.50) | HCAR1TNFLITAFPIK3CACTSD | |
| SCHEMBL25152012 | 0.76 | USP30 (0.37) | USP30HCAR1BACE1 | |
| SCHEMBL15206849 | 0.76 | USP30 (0.51) | USP30HCAR1CTSDCTSEBACE1 | |
| SCHEMBL18136675 | 0.76 | USP30 (0.51) | USP30HCAR1SRCEGFRABL1 | |
| SCHEMBL3663578 | 0.75 | USP30 (0.51) | USP30HCAR1SRCEGFRABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064880-A1 | COMPOUNDS AND METHODS FOR MODULATING NUCLEIC ACID SPLICING | REMIX THERAPEUTICS INC. (US) | 2023-04-20 | — | — | WO | disclosed |