Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 2/20 | 0.38 |
| ▸ | LITAF | Q99732 | 2/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30400063 | 1.00 | USP30 (0.42) | USP30PDE4BFPR2TP53KDM4E | |
| SCHEMBL21593334 | 0.80 | SIK1 (0.42) | KDM4EMAPTMEN1KMT2A | |
| SCHEMBL29693114 | 0.78 | USP30 (0.38) | USP30PDE4BFPR2TP53STS | |
| SCHEMBL24558077 | 0.78 | USP30 (0.38) | USP30PDE4BFPR2TP53STS | |
| SCHEMBL20134975 | 0.78 | PIK3CA (0.46) | USP30FPR2KDM4EMAPTTHRB | |
| SCHEMBL4106892 | 0.78 | FPR2 (0.46) | USP30FPR2KDM4EMAPTTHRB | |
| SCHEMBL8230370 | 0.77 | HRH3 (0.49) | USP30TP53GPR119PIK3CASTS | |
| SCHEMBL30398870 | 0.75 | PIK3CA (0.37) | USP30GPR119PIK3CATNFLITAF | |
| SCHEMBL23761149 | 0.74 | PIK3CA (0.44) | USP30FPR2TP53KDM4EMAPT | |
| SCHEMBL26506272 | 0.74 | PIK3CA (0.44) | USP30FPR2TP53KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064880-A1 | COMPOUNDS AND METHODS FOR MODULATING NUCLEIC ACID SPLICING | REMIX THERAPEUTICS INC. (US) | 2023-04-20 | — | — | WO | disclosed |