Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.49 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | CTSE | P14091 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25151029 | 0.87 | HCAR1 (0.51) | HCAR1DPP4GPR119KDM4EMAPT | |
| SCHEMBL25150890 | 0.81 | HCAR1 (0.45) | HCAR1DPP4SYK | |
| SCHEMBL25151102 | 0.81 | HCAR1 (0.45) | HCAR1DPP4GPR119KDM4EMAPT | |
| SCHEMBL30186870 | 0.79 | HCAR1 (0.44) | HCAR1GPR119SYKCTSDCTSE | |
| SCHEMBL30186868 | 0.79 | HCAR1 (0.44) | HCAR1GPR119SYKCTSDCTSE | |
| SCHEMBL30186797 | 0.79 | HCAR1 (0.44) | HCAR1DPP4GPR119SYK | |
| SCHEMBL30186827 | 0.78 | HCAR1 (0.43) | HCAR1GPR119SYK | |
| SCHEMBL30399526 | 0.78 | HCAR1 (0.52) | HCAR1GPR119KDM4EMAPTTHRB | |
| SCHEMBL30186821 | 0.77 | HCAR1 (0.42) | HCAR1DPP4GPR119SYK | |
| SCHEMBL30186829 | 0.77 | HCAR1 (0.41) | HCAR1GPR119SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064880-A1 | COMPOUNDS AND METHODS FOR MODULATING NUCLEIC ACID SPLICING | REMIX THERAPEUTICS INC. (US) | 2023-04-20 | — | — | WO | disclosed |