Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 4/20 | 0.75 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.59 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.58 |
| ▸ | RXRA | P19793 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | APEX1 | P27695 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | STAT3 | P40763 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.51 |
| ▸ | EP300 | Q09472 | 1/20 | 0.50 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3897009 | 0.89 | MAP3K5 (0.87) | MAP3K5DUSP3MAPTAPEX1MEN1 | |
| SCHEMBL3897012 | 0.89 | MAP3K5 (0.87) | MAP3K5DUSP3MAPTAPEX1MEN1 | |
| SCHEMBL3490464 | 0.88 | MAPT (0.71) | MAP3K5DUSP3TNFRSF1ARXRAMAPT | |
| SCHEMBL25151938 | 0.88 | STAT3 (0.61) | MAP3K5TNFRSF1AMAPTPOLBALDH1A1 | |
| SCHEMBL3490465 | 0.88 | MAPT (0.71) | MAP3K5DUSP3TNFRSF1ARXRAMAPT | |
| SCHEMBL3908073 | 0.88 | MAP3K5 (0.69) | MAP3K5DUSP3TNFRSF1ARXRAMAPT | |
| SCHEMBL3908078 | 0.88 | MAP3K5 (0.69) | MAP3K5DUSP3TNFRSF1ARXRAMAPT | |
| SCHEMBL25152930 | 0.87 | MAP3K5 (0.62) | MAP3K5DUSP3TNFRSF1AMAPTAPEX1 | |
| SCHEMBL3897422 | 0.87 | MAP3K5 (0.78) | MAP3K5MAPTAPEX1POLBALDH1A1 | |
| SCHEMBL3890923 | 0.87 | MAP3K5 (0.70) | MAP3K5DUSP3TNFRSF1ARXRAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064368-A1 | NOVEL RHODANINE DERIVATIVES AND USES THEREOF | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2023-04-20 | — | — | WO | disclosed |