Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | POLB | P06746 | 3/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | RAB9A | P51151 | 1/20 | 0.71 |
| ▸ | MAP3K5 | Q99683 | 4/20 | 0.66 |
| ▸ | RXRA | P19793 | 1/20 | 0.61 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3490464 | 1.00 | MAPT (0.71) | MAPTALDH1A1POLBLMNARAB9A | |
| SCHEMBL25152806 | 0.88 | MAP3K5 (0.75) | MAPTALDH1A1POLBLMNARAB9A | |
| SCHEMBL15106999 | 0.85 | MAPT (0.77) | MAPTALDH1A1POLBLMNARAB9A | |
| SCHEMBL15317957 | 0.85 | MAPT (0.77) | MAPTALDH1A1POLBLMNARAB9A | |
| SCHEMBL13326261 | 0.84 | MAP3K5 (0.58) | MAPTALDH1A1POLBLMNARAB9A | |
| SCHEMBL3896235 | 0.84 | POLB (0.75) | MAPTALDH1A1POLBLMNARAB9A | |
| SCHEMBL7852520 | 0.84 | MAPT (0.75) | MAPTALDH1A1POLBLMNARAB9A | |
| SCHEMBL3896239 | 0.84 | POLB (0.75) | MAPTALDH1A1POLBLMNARAB9A | |
| SCHEMBL3908073 | 0.83 | MAP3K5 (0.69) | MAPTALDH1A1POLBLMNARAB9A | |
| SCHEMBL3908078 | 0.83 | MAP3K5 (0.69) | MAPTALDH1A1POLBLMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8486863-B2 | Activators of lateral root formation | VIB VZW (BE) | 2013-07-16 | — | — | US | claimed |
| US-20100105561-A1 | ACTIVATORS OF LATERAL ROOT FORMATION | UNIVERSITEIT GENT (BE) | 2010-04-29 | — | — | US | claimed |
| EP-2094082-A2 | ACTIVATORS OF LATERAL ROOT FORMATION | VIB VZW (BE) | 2009-09-02 | — | — | EP | claimed |
| US-20090137644-A1 | RHODANINE COMPOSITIONS FOR USE AS ANTIVIRAL AGENTS | RIGEL PHARMACEUTICALS, INC. (US) | 2009-05-28 | — | — | US | claimed |
| WO-2008062035-A2 | ACTIVATORS OF LATERAL ROOT FORMATION | VIB VZW (BE) | 2008-05-29 | — | — | WO | claimed |
| WO-2005041951-A2 | RHODANINE DERIVATIVES FOR USE AS ANTIVIRAL AGENTS | RIGEL PHARMACEUTICALS, INC. (US) | 2005-05-12 | — | — | WO | claimed |
| US-8486863-B2 | Activators of lateral root formation | VIB VZW (BE) | 2013-07-16 | — | — | US | disclosed |
| US-20100105561-A1 | ACTIVATORS OF LATERAL ROOT FORMATION | UNIVERSITEIT GENT (BE) | 2010-04-29 | — | — | US | disclosed |
| EP-2094082-A2 | ACTIVATORS OF LATERAL ROOT FORMATION | VIB VZW (BE) | 2009-09-02 | — | — | EP | disclosed |
| US-7566732-B2 | Rhodanine compositions for use as antiviral agents | RIGEL PHARMACEUTICALS, INC. (US) | 2009-07-28 | — | — | US | disclosed |
| US-20090137644-A1 | RHODANINE COMPOSITIONS FOR USE AS ANTIVIRAL AGENTS | RIGEL PHARMACEUTICALS, INC. (US) | 2009-05-28 | — | — | US | disclosed |
| WO-2008062035-A2 | ACTIVATORS OF LATERAL ROOT FORMATION | VIB VZW (BE) | 2008-05-29 | — | — | WO | disclosed |
| US-20060276520-A1 | Rhodanine derivatives and pharmaceutical compositions containing them | RIGEL PHARMACEUTICALS, INC. (US) | 2006-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105561-A1 | ACTIVATORS OF LATERAL ROOT FORMATION | CROCC, ARFIP2, RALA | MAPT 4049/4885ALDH1A1 3385/4885POLB 3799/4885 |
| US-20060276520-A1 | Rhodanine derivatives and pharmaceutical compositions containing them | UBQLN1, UBQLN2, UBE2G2 | MAPT 1187/4885ALDH1A1 1828/4885POLB 2008/4885 |
| US-20090137644-A1 | RHODANINE COMPOSITIONS FOR USE AS ANTIVIRAL AGENTS | RBX1, ITCH, UBQLN1 | MAPT 880/4885ALDH1A1 3199/4885POLB 433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.