Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.57 |
| ▸ | CA1 | P00915 | 5/20 | 0.57 |
| ▸ | CA2 | P00918 | 5/20 | 0.57 |
| ▸ | CA9 | Q16790 | 5/20 | 0.57 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.53 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | ITK | Q08881 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30343966 | 1.00 | CA12 (0.57) | CA12CA1CA2CA9PDK2 | |
| SCHEMBL13162913 | 0.96 | CA12 (0.58) | CA12CA1CA2CA9PDK2 | |
| SCHEMBL13162350 | 0.91 | CA12 (0.56) | CA12CA1CA2CA9PDK2 | |
| SCHEMBL16504682 | 0.91 | CA12 (0.58) | CA12CA1CA2CA9PDK2 | |
| SCHEMBL30344719 | 0.89 | CA12 (0.56) | CA12CA1CA2CA9PDK2 | |
| SCHEMBL25155339 | 0.89 | CA12 (0.56) | CA12CA1CA2CA9PDK2 | |
| SCHEMBL21601451 | 0.87 | CA12 (0.62) | CA12CA1CA2CA9PDK2 | |
| SCHEMBL13162402 | 0.85 | CA12 (0.57) | CA12CA1CA2CA9PDK2 | |
| SCHEMBL21601198 | 0.84 | CA12 (0.60) | CA12CA1CA2CA9PDK2 | |
| SCHEMBL26518326 | 0.84 | BCHE (0.52) | CA12CA1CA2CA9PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064493-A1 | COMPOUNDS AND METHODS FOR TREATING CORONAVIRUSES | Clear Creek Bio, Inc. (US) | 2023-04-20 | — | — | WO | disclosed |