Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.58 |
| ▸ | CA1 | P00915 | 5/20 | 0.58 |
| ▸ | CA2 | P00918 | 5/20 | 0.58 |
| ▸ | CA9 | Q16790 | 5/20 | 0.58 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26518326 | 0.93 | BCHE (0.52) | CA12CA1CA2CA9PDK2 | |
| SCHEMBL19475821 | 0.92 | CA12 (0.60) | CA12CA1CA2CA9PDK2 | |
| SCHEMBL20919690 | 0.91 | CA12 (0.61) | CA12CA1CA2CA9PDK2 | |
| SCHEMBL25155264 | 0.91 | CA12 (0.57) | CA12CA1CA2CA9PDK2 | |
| SCHEMBL30343966 | 0.91 | CA12 (0.57) | CA12CA1CA2CA9PDK2 | |
| SCHEMBL13162350 | 0.90 | CA12 (0.56) | CA12CA1CA2CA9PDK2 | |
| SCHEMBL13162913 | 0.87 | CA12 (0.58) | CA12CA1CA2CA9PDK2 | |
| SCHEMBL16520527 | 0.87 | CA12 (0.58) | CA12CA1CA2CA9PDK2 | |
| SCHEMBL16522121 | 0.86 | CA12 (0.57) | CA12CA1CA2CA9PDK2 | |
| SCHEMBL7399614 | 0.84 | CA12 (0.55) | CA12CA1CA2CA9PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3035923-B1 | DITHIOL MUCOLYTIC AGENTS | PARION SCIENCES INC (US) | 2019-09-25 | — | — | EP | disclosed |
| US-9963427-B2 | Dithiol mucolytic agents | PARION SCIENCES, INC. (US) | 2018-05-08 | — | — | US | disclosed |
| US-20160318861-A1 | NOVEL PRODRUGS OF DITHIOL MUCOLYTIC AGENTS | PARION SCIENCES, INC. (US) | 2016-11-03 | — | — | US | disclosed |
| US-20160194278-A1 | DITHIOL MUCOLYTIC AGENTS | PARION SCIENCES, INC. (US) | 2016-07-07 | — | — | US | disclosed |
| EP-3035923-A2 | DITHIOL MUCOLYTIC AGENTS | Parion Sciences, Inc. (US) | 2016-06-29 | — | — | EP | disclosed |
| US-9346753-B2 | Dithiol mucolytic agents | PARION SCIENCES, INC. (US) | 2016-05-24 | — | — | US | disclosed |
| WO-2015026601-A2 | DITHIOL MUCOLYTIC AGENTS | JOHNSON MICHAEL R (US) | 2015-02-26 | — | — | WO | disclosed |
| US-20150056305-A1 | DITHIOL MUCOLYTIC AGENTS | PARION SCIENCES, INC. (US) | 2015-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160194278-A1 | DITHIOL MUCOLYTIC AGENTS | MUC1, DNASE1, MMP8 | CA12 176/4885CA1 566/4885CA2 1000/4885 |
| US-20150056305-A1 | DITHIOL MUCOLYTIC AGENTS | MUC1, DNASE1, MMP8 | CA12 176/4885CA1 566/4885CA2 1000/4885 |
| US-20160318861-A1 | NOVEL PRODRUGS OF DITHIOL MUCOLYTIC AGENTS | MUC1, MGMT, ESD | CA12 319/4885CA1 624/4885CA2 2098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.