Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ITK | Q08881 | 1/20 | 0.39 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30344073 | 1.00 | PDK2 (0.49) | PDK2CA12CA1CA2CA9 | |
| SCHEMBL30344922 | 0.97 | PDK2 (0.47) | PDK2CA12CA1CA2CA9 | |
| SCHEMBL25155179 | 0.97 | PDK2 (0.47) | PDK2CA12CA1CA2CA9 | |
| SCHEMBL30344146 | 0.90 | PDK2 (0.47) | PDK2CA12CA1CA2CA9 | |
| SCHEMBL31359914 | 0.90 | PDK2 (0.47) | PDK2CA12CA1CA2CA9 | |
| SCHEMBL25155930 | 0.90 | PDK2 (0.47) | PDK2CA12CA1CA2CA9 | |
| SCHEMBL25155451 | 0.89 | KDM4E (0.47) | PDK2 | |
| SCHEMBL30344711 | 0.89 | KDM4E (0.47) | PDK2 | |
| SCHEMBL25156505 | 0.88 | PDK2 (0.45) | PDK2CA12CA1CA2CA9 | |
| SCHEMBL30344131 | 0.88 | PDK2 (0.45) | PDK2CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064493-A1 | COMPOUNDS AND METHODS FOR TREATING CORONAVIRUSES | Clear Creek Bio, Inc. (US) | 2023-04-20 | — | — | WO | disclosed |