SCHEMBL30344922

SCHEMBL30344922

Cc1ccc(OCCCNC(=O)OC(C)(C)C)cc1C(=O)NC1(c2cccc3ccccc23)CC1

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 1/20 0.47
CA12 O43570 5/20 0.42
CA1 P00915 5/20 0.42
CA2 P00918 5/20 0.42
CA9 Q16790 5/20 0.42
EGFR P00533 2/20 0.42
ITK Q08881 2/20 0.42
SUCNR1 Q9BXA5 4/20 0.41
NQO2 P16083 1/20 0.39
BRD4 O60885 1/20 0.38
BCHE P06276 1/20 0.38
CNR2 P34972 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25155179 1.00 PDK2 (0.47) PDK2CA12CA1CA2CA9
SCHEMBL25155491 0.97 PDK2 (0.49) PDK2CA12CA1CA2CA9
SCHEMBL30344073 0.97 PDK2 (0.49) PDK2CA12CA1CA2CA9
SCHEMBL25155930 0.88 PDK2 (0.47) PDK2CA12CA1CA2CA9
SCHEMBL31359914 0.88 PDK2 (0.47) PDK2CA12CA1CA2CA9
SCHEMBL30344146 0.88 PDK2 (0.47) PDK2CA12CA1CA2CA9
SCHEMBL25155451 0.87 KDM4E (0.47) PDK2
SCHEMBL30344711 0.87 KDM4E (0.47) PDK2
SCHEMBL25155891 0.87 HTR1D (0.40) PDK2
SCHEMBL30344152 0.87 HTR1D (0.40) PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250025443-A1 COMPOUNDS AND METHODS FOR TREATING CORONA VIRUSES Clear Creek Bio, Inc. (US) 2025-01-23 US disclosed
WO-2023064493-A1 COMPOUNDS AND METHODS FOR TREATING CORONAVIRUSES Clear Creek Bio, Inc. (US) 2023-04-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250025443-A1 COMPOUNDS AND METHODS FOR TREATING CORONA VIRUSES ACE, PREP, PEPD PDK2 3215/4885CA12 697/4885CA1 548/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.