Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 7/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30344108 | 1.00 | AKT1 (0.42) | AKT1MEN1KMT2ANPC1GAA | |
| SCHEMBL31360275 | 1.00 | AKT1 (0.42) | AKT1MEN1KMT2ANPC1GAA | |
| SCHEMBL18991860 | 0.84 | SSTR4 (0.39) | AKT1MEN1KMT2ANPC1GAA | |
| SCHEMBL27478229 | 0.83 | AKT1 (0.46) | AKT1RAB9AP2RX7SSTR4 | |
| SCHEMBL31360207 | 0.82 | MEN1 (0.43) | AKT1MEN1KMT2ANPC1GAA | |
| SCHEMBL25156432 | 0.82 | MEN1 (0.43) | AKT1MEN1KMT2ANPC1GAA | |
| SCHEMBL30344792 | 0.82 | MEN1 (0.43) | AKT1MEN1KMT2ANPC1GAA | |
| SCHEMBL27088912 | 0.81 | POLB (0.44) | AKT1GAARAB9AP2RX7SMN1; SMN2 | |
| SCHEMBL147469 | 0.79 | AKT1 (0.42) | AKT1MEN1KMT2ANPC1GAA | |
| SCHEMBL25156505 | 0.78 | PDK2 (0.45) | MEN1KMT2AP2RX7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064493-A1 | COMPOUNDS AND METHODS FOR TREATING CORONAVIRUSES | Clear Creek Bio, Inc. (US) | 2023-04-20 | — | — | WO | disclosed |