Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 4/20 | 0.41 |
| ▸ | ACACA | Q13085 | 3/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | TOP2A | P11388 | 1/20 | 0.35 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 2/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31360207 | 1.00 | MEN1 (0.43) | MEN1NPC1GAARAB9AKMT2A | |
| SCHEMBL25156432 | 1.00 | MEN1 (0.43) | MEN1NPC1GAARAB9AKMT2A | |
| SCHEMBL30964809 | 0.86 | ACACB (0.51) | MEN1NPC1GAARAB9AKMT2A | |
| SCHEMBL30344108 | 0.82 | AKT1 (0.42) | MEN1NPC1GAARAB9AKMT2A | |
| SCHEMBL31360275 | 0.82 | AKT1 (0.42) | MEN1NPC1GAARAB9AKMT2A | |
| SCHEMBL25155751 | 0.82 | AKT1 (0.42) | MEN1NPC1GAARAB9AKMT2A | |
| SCHEMBL30344873 | 0.77 | HDAC3 (0.42) | CNR1CNR2AKT1LCKSLC6A4 | |
| SCHEMBL25156271 | 0.77 | HDAC3 (0.42) | CNR1CNR2AKT1LCKSLC6A4 | |
| SCHEMBL27088912 | 0.76 | POLB (0.44) | GAARAB9AP2RX7KDM4ECNR1 | |
| SCHEMBL30890423 | 0.74 | AKT1 (0.39) | MEN1NPC1GAARAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064493-A1 | COMPOUNDS AND METHODS FOR TREATING CORONAVIRUSES | Clear Creek Bio, Inc. (US) | 2023-04-20 | — | — | WO | disclosed |