Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30344873 | 1.00 | HDAC3 (0.42) | HDAC3HDAC1HDAC2HDAC6HDAC4 | |
| SCHEMBL30890423 | 0.85 | AKT1 (0.39) | MAPK10AKT1LMNAGHSRPOLB | |
| SCHEMBL22615404 | 0.83 | NPC1 (0.46) | MAPK10AKT1GHSR | |
| SCHEMBL29425122 | 0.83 | NPC1 (0.46) | MAPK10AKT1GHSR | |
| SCHEMBL30537895 | 0.82 | MEN1 (0.39) | MAPK10AKT1GHSR | |
| SCHEMBL30344367 | 0.82 | HDAC4 (0.46) | HDAC4MAPK10AKT1DRD2LMNA | |
| SCHEMBL25156176 | 0.82 | HDAC4 (0.46) | HDAC4MAPK10AKT1DRD2LMNA | |
| SCHEMBL27088912 | 0.81 | POLB (0.44) | CNR1CNR2AKT1DRD2LMNA | |
| SCHEMBL31115209 | 0.81 | ATR (0.38) | ROCK2CNR1CNR2AKT1DRD2 | |
| SCHEMBL18981959 | 0.81 | ATR (0.38) | ROCK2CNR1CNR2AKT1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064493-A1 | COMPOUNDS AND METHODS FOR TREATING CORONAVIRUSES | Clear Creek Bio, Inc. (US) | 2023-04-20 | — | — | WO | disclosed |