SCHEMBL30344367

SCHEMBL30344367

CCc1ccccc1C1(NC(=O)OC(C)(C)C)CC1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 1/20 0.46
GHSR Q92847 1/20 0.40
AKT1 P31749 3/20 0.39
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA7 P43166 1/20 0.37
CA14 Q9ULX7 1/20 0.37
DPP8 Q6V1X1 1/20 0.36
DPP9 Q86TI2 1/20 0.36
PDK2 Q15119 2/20 0.36
MAPK10 P53779 1/20 0.36
LMNA P02545 1/20 0.36
POLB P06746 1/20 0.36
DRD2 P14416 1/20 0.36
ALDH1A1 P00352 1/20 0.36
TSHR P16473 1/20 0.36
APLNR P35414 1/20 0.35
KDM4A O75164 1/20 0.35
EPHX2 P34913 1/20 0.35
PPARG P37231 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25156176 1.00 HDAC4 (0.46) HDAC4GHSRAKT1CA12CA1
SCHEMBL30890423 0.84 AKT1 (0.39) GHSRAKT1CA12CA1CA7
SCHEMBL30344873 0.82 HDAC3 (0.42) HDAC4GHSRAKT1MAPK10LMNA
SCHEMBL29425122 0.82 NPC1 (0.46) GHSRAKT1CA12CA1CA7
SCHEMBL25156271 0.82 HDAC3 (0.42) HDAC4GHSRAKT1MAPK10LMNA
SCHEMBL22615404 0.82 NPC1 (0.46) GHSRAKT1CA12CA1CA7
SCHEMBL30537895 0.81 MEN1 (0.39) GHSRAKT1CA12CA1CA7
SCHEMBL25156100 0.80 AKT1 (0.43) AKT1CA12CA1CA7CA14
SCHEMBL31359913 0.80 LPAR1 (0.39) AKT1TSHR
SCHEMBL30463159 0.80 PDK2 (0.43) AKT1CA1PDK2LMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250025443-A1 COMPOUNDS AND METHODS FOR TREATING CORONA VIRUSES Clear Creek Bio, Inc. (US) 2025-01-23 US disclosed
WO-2023064493-A1 COMPOUNDS AND METHODS FOR TREATING CORONAVIRUSES Clear Creek Bio, Inc. (US) 2023-04-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250025443-A1 COMPOUNDS AND METHODS FOR TREATING CORONA VIRUSES ACE, PREP, PEPD HDAC4 2354/4885GHSR 4213/4885AKT1 4880/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.