Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | NQO1 | P15559 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30344621 | 1.00 | CDC25B (0.47) | CDC25BCYP1A2CYP2A6UGT2B7CASP3 | |
| SCHEMBL20314895 | 0.86 | CYP1A2 (0.53) | CDC25BCYP1A2CYP2A6CASP3SENP7 | |
| SCHEMBL3929101 | 0.81 | CYP2D6 (0.50) | CYP1A2CYP2A6CYP2D6ADRA2AADRA1A | |
| SCHEMBL3929104 | 0.81 | CYP2D6 (0.50) | CYP1A2CYP2A6CYP2D6ADRA2AADRA1A | |
| SCHEMBL31581619 | 0.77 | CDC25B (0.49) | CDC25BCYP1A2GPR84 | |
| SCHEMBL21120749 | 0.77 | CYP1A2 (0.53) | CYP1A2CYP2A6UGT2B7NQO2KDM2B | |
| SCHEMBL31524012 | 0.76 | CDC25B (0.48) | CDC25BCYP1A2CASP3SENP7GPR84 | |
| SCHEMBL16033860 | 0.76 | TRPM4 (0.48) | CYP1A2CYP2A6UGT2B7NQO2CYP2D6 | |
| SCHEMBL911036 | 0.74 | NQO2 (0.61) | CDC25BCYP1A2CYP2A6CASP3SENP7 | |
| SCHEMBL29428606 | 0.74 | NQO2 (0.61) | CDC25BCYP1A2CYP2A6CASP3SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064493-A1 | COMPOUNDS AND METHODS FOR TREATING CORONAVIRUSES | Clear Creek Bio, Inc. (US) | 2023-04-20 | — | — | WO | disclosed |