Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KRAS | P01116 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3929104 | 1.00 | CYP2D6 (0.50) | CYP2D6CYP1A2CYP2A6MTNR1AMTNR1B | |
| SCHEMBL1901839 | 0.87 | MTNR1A (0.59) | CYP1A2CYP2A6MTNR1AMTNR1BKRAS | |
| SCHEMBL14242763 | 0.86 | CYP1A2 (0.57) | CYP2D6CYP1A2CYP2A6MTNR1AMTNR1B | |
| SCHEMBL21562577 | 0.83 | CYP1A2 (0.48) | CYP2D6CYP1A2CYP2A6MTNR1AMTNR1B | |
| SCHEMBL11275219 | 0.83 | CYP1A2 (0.48) | CYP2D6CYP1A2CYP2A6MTNR1AMTNR1B | |
| SCHEMBL29123896 | 0.83 | CYP1A2 (0.48) | CYP2D6CYP1A2CYP2A6MTNR1AMTNR1B | |
| SCHEMBL11739561 | 0.83 | CYP2D6 (0.48) | CYP2D6CYP1A2CYP2A6MTNR1AMTNR1B | |
| SCHEMBL3930770 | 0.83 | MTNR1A (0.52) | CYP2D6CYP1A2CYP2A6MTNR1AMTNR1B | |
| SCHEMBL3930766 | 0.83 | MTNR1A (0.52) | CYP2D6CYP1A2CYP2A6MTNR1AMTNR1B | |
| SCHEMBL7031139 | 0.81 | PTGS2 (0.57) | CYP1A2MTNR1AMTNR1BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117776902-A | Preparation method of naproxen | 帕潘纳(北京)科技有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-117229137-A | Method for preparing naproxen | 帕潘纳(北京)科技有限公司 | 2023-12-15 | — | — | CN | disclosed |
| EP-1934159-B1 | METHOD FOR FRACTIONATING STEREOISOMERIC COMPOUNDS | BASF SE (DE) | 2009-03-25 | — | — | EP | disclosed |
| US-20090030235-A1 | METHOD FOR FRACTIONATING STEREOISOMERIC COMPOUNDS | BASF SE (DE) | 2009-01-29 | — | — | US | disclosed |
| EP-1934159-A1 | METHOD FOR FRACTIONATING STEREOISOMERIC COMPOUNDS | BASF SE (DE) | 2008-06-25 | — | — | EP | disclosed |
| WO-2007036570-A1 | METHOD FOR FRACTIONATING STEREOISOMERIC COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2007-04-05 | — | — | WO | disclosed |
| US-20050283020-A1 | Process for the preparation of 2-aryl propionic acids | CHAUDHARI RAGHUNATH V | 2005-12-22 | — | — | US | disclosed |
| EP-1505156-B1 | Process for the enantioselective preparation of secondary alcohols by lipase catalysed solvolysis of the corresponding acetoacetic acid ester | CONSORTIUM ELEKTROCHEM IND (DE) | 2005-12-07 | — | — | EP | disclosed |
| US-20050032182-A1 | Process for the enantioselective preparation of secondary alcohols by lipase-catalyzed solvolysis of the corresponding acetoacetic esters | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH | 2005-02-10 | — | — | US | disclosed |
| EP-1505156-A1 | Process for the enantioselective preparation of secondary alcohols by lipase catalysed solvolysis of the corresponding acetoacetic acid ester | Consortium für elektrochemische Industrie GmbH (DE) | 2005-02-09 | — | — | EP | disclosed |
| US-6660883-B1 | Conversion of aryl alkyl compound such as aryl alkyl alcohols and aryl alkyl halides | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2003-12-09 | — | — | US | disclosed |
| US-6365398-B1 | REACTING RACEMIC CARBOXYLIC ACID ESTER WITH RACEMIC ALCOHOL IN PRESENCE OF A CARBOXYL ESTER HYDROLASE | BASF AKTIENGESELLSCHAFT (DE) | 2002-04-02 | — | — | US | disclosed |
| EP-1031629-A2 | Method of preparation of stereoisomeric carboxylic acid esters | BASF AKTIENGESELLSCHAFT (DE) | 2000-08-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090030235-A1 | METHOD FOR FRACTIONATING STEREOISOMERIC COMPOUNDS | ADH5, ADH1C, ADH1A | CYP2D6 82/4885CYP1A2 65/4885CYP2A6 45/4885 |
| US-20050283020-A1 | Process for the preparation of 2-aryl propionic acids | ADH1C, ADH5, ADH1A | CYP2D6 194/4885CYP1A2 53/4885CYP2A6 32/4885 |
| US-20050032182-A1 | Process for the enantioselective preparation of secondary alcohols by lipase-catalyzed solvolysis of the corresponding acetoacetic esters | LIPC, LIPE, LIPA | CYP2D6 807/4885CYP1A2 453/4885CYP2A6 296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.