SCHEMBL2515769

SCHEMBL2515769

CCCCOOC(=O)c1ccccc1.CCCCOOC(=O)c1ccccc1.[Zr]

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.56
F2 P00734 1/20 0.53
TSHR P16473 8/20 0.50
TDP1 Q9NUW8 4/20 0.50
L3MBTL1 Q9Y468 3/20 0.50
MAPK1 P28482 3/20 0.47
CYP1A2 P05177 2/20 0.47
CYP2C19 P33261 2/20 0.47
ESR1 P03372 1/20 0.47
CYP2D6 P10635 1/20 0.47
NR1H2 P55055 1/20 0.47
RNASEL Q05823 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
ALDH1A1 P00352 4/20 0.47
HSD17B10 Q99714 2/20 0.47
CYP3A4 P08684 3/20 0.46
CYP2C9 P11712 1/20 0.46
PDE4D Q08499 1/20 0.46
CES2 O00748 3/20 0.46
CES1 P23141 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL98564 0.98 LMNA (0.58) LMNAF2TSHRTDP1L3MBTL1
Benzoyl Peroxide SCHEMBL10537673 0.97 LMNA (0.59) LMNAF2TSHRTDP1L3MBTL1
SCHEMBL28161778 0.95 LMNA (0.54) LMNAF2TSHRTDP1L3MBTL1
Benzoic Acid SCHEMBL9668494 0.93 LMNA (0.53) LMNAF2TSHRTDP1L3MBTL1
SCHEMBL5133899 0.93 LMNA (0.56) LMNAF2TSHRTDP1MAPK1
SCHEMBL5076640 0.92 LMNA (0.51) LMNAF2TSHRTDP1L3MBTL1
Formic Acid SCHEMBL27904266 0.92 LMNA (0.51) LMNAF2TSHRTDP1L3MBTL1
O-Xylene SCHEMBL6529711 0.92 LMNA (0.51) LMNAF2TSHRTDP1L3MBTL1
SCHEMBL825240 0.92 LMNA (0.54) LMNAF2TSHRTDP1MAPK1
SCHEMBL6462426 0.92 LMNA (0.54) LMNAF2TSHRTDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9051435-B2 Silanol condensation catalyst, heat-curable silicone resin composition for sealing photosemiconductors and sealed photosemiconductor using same THE YOKOHAMA RUBBER CO., LTD. (JP) 2015-06-09 US disclosed
US-20140256539-A1 SILANOL CONDENSATION CATALYST, HEAT-CURABLE SILICONE RESIN COMPOSITION FOR SEALING PHOTOSEMICONDUCTORS AND SEALED PHOTOSEMICONDUCTOR USING SAME THE YOKOHAMA RUBBER CO., LTD. (JP) 2014-09-11 US disclosed
US-8772431-B2 Silanol condensation catalyst, heat-curable silicone resin composition for sealing photosemiconductors and sealed photosemiconductor using same THE YOKOHAMA RUBBER CO., LTD. (JP) 2014-07-08 US disclosed
US-8669583-B2 Heat-curable silicone resin composition for sealing optical semiconductors, and a sealed optical semiconductor using the same THE YOKOHAMA RUBBER CO., LTD. (JP) 2014-03-11 US disclosed
US-20120211797-A1 HEAT-CURABLE SILICONE RESIN COMPOSITION FOR SEALING OPTICAL SEMICONDUCTORS, AND A SEALED OPTICAL SEMICONDUCTOR USING THE SAME THE YOKOHAMA RUBBER CO., LTD. (JP) 2012-08-23 US disclosed
US-20110248314-A1 SILANOL CONDENSATION CATALYST, HEAT-CURABLE SILICONE RESIN COMPOSITION FOR SEALING PHOTOSEMICONDUCTORS AND SEALED PHOTOSEMICONDUCTOR USING SAME THE YOKOHAMA RUBBER CO., LTD. (JP) 2011-10-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110248314-A1 SILANOL CONDENSATION CATALYST, HEAT-CURABLE SILICONE RESIN COMPOSITION FOR SEALING PHOTOSEMICONDUCTORS AND SEALED PHOTOSEMICONDUCTOR USING SAME ASH2L, RCOR1, SEM1 LMNA 1499/4885F2 3740/4885TSHR 4322/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.