⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9316734 | 0.52 | — | — | |
| Formic Acid SCHEMBL25243578 | 0.38 | — | — | |
| Formic Acid SCHEMBL30451461 | 0.38 | — | — | |
| Benzene SCHEMBL2295857 | 0.38 | — | — | |
| Formic Acid SCHEMBL15260417 | 0.38 | ALDH1A1 (0.38) | — | |
| Formic Acid SCHEMBL1331809 | 0.38 | — | — | |
| Formic Acid SCHEMBL29399448 | 0.38 | — | — | |
| Formic Acid SCHEMBL181555 | 0.38 | — | — | |
| Formic Acid SCHEMBL6682610 | 0.38 | ALDH1A1 (0.38) | — | |
| Formic Acid SCHEMBL11248324 | 0.38 | ALDH1A1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119350315-A | 2- (1H-indole-2-yl) -1,3, 4-oxadiazole derivatives, and preparation method and application thereof | 南开大学 | 2025-01-24 | — | — | CN | claimed |
| CN-119350315-A | 2- (1H-indole-2-yl) -1,3, 4-oxadiazole derivatives, and preparation method and application thereof | 南开大学 | 2025-01-24 | — | — | CN | disclosed |
| CN-115884810-A | Imidazopyridazines as IL-17 modulators | 詹森药业有限公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-110099901-A | Pyrazolo [3,4-b] pyridine and imidazo [1,5-b] pyridazine as PDE1 inhibitor | H.隆德贝克有限公司 | 2019-08-06 | — | — | CN | disclosed |
| CN-109311872-A | 1H- pyrazolo [4,3-b] pyridine as PDE1 inhibitor | H.隆德贝克有限公司 | 2019-02-05 | — | — | CN | disclosed |
| CN-103200820-A | Novel substituted quinoline compounds as S-nitrosoglutathione reductase inhibitors | N30 PHARMACEUTICALS LLC | 2013-07-10 | — | — | CN | disclosed |
| EP-2379524-A1 | SEROTONIN 5-HT2B RECEPTOR INHIBITORS | Boehringer Ingelheim International GmbH (DE) | 2011-10-26 | — | — | EP | disclosed |
| CN-101870690-A | The prevention and the treatment that are substituted aryl and heteroaryl derivative and associated conditions thereof as metabolism regulators | ARENA PHARM INC | 2010-10-27 | — | — | CN | disclosed |
| WO-2010080357-A1 | SEROTONIN 5-HT2B RECEPTOR INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-07-15 | — | — | WO | disclosed |
| CN-100424078-C | Pyrimidine-2, 4-dione derivatives as gonadotropin-releasing hormone receptor antagonists | NEUROCRINE BIOSCIENCES INC (US) | 2008-10-08 | — | — | CN | disclosed |
| CN-101229165-A | Pyrimidine-2,4-dione derivatives as gonadotropin-releasing hormone receptor antagonists | NEUROCRINE BIOSCIENCES INC (US) | 2008-07-30 | — | — | CN | disclosed |
| CN-100376246-C | Pyrimidine-2, 4-dione derivatives as gonadotropin-releasing hormone receptor antagonists | NEUROCRINE BIOSCIENCES INC (US) | 2008-03-26 | — | — | CN | disclosed |
| CN-1997640-A | Substituted aryl and heteroaryl derivatives as modulators of metabolism and the prevention and treatment of disorders related thereto | ARENA PHARM INC (US) | 2007-07-11 | — | — | CN | disclosed |
| CN-1826119-A | Pyrimidine-2, 4-dione derivatives as gonadotropin-releasing hormone receptor antagonists | NEUROCRINE BIOSCIENCES INC (US) | 2006-08-30 | — | — | CN | disclosed |
| CN-1819829-A | Pyrimidine-2, 4-dione derivatives as gonadotropin-releasing hormone receptor antagonists | NEUROCRINE BIOSCIENCES INC (US) | 2006-08-16 | — | — | CN | disclosed |
| CN-1691944-A | Oxadiazoles as modulators of metabotropic glutamate receptor-5 | ASTRAZENECA AB (SE) | 2005-11-02 | — | — | CN | disclosed |